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Kicking latent HIV: New strategies to reactivate reservoirs of latent infection

In cells with latent HIV infection, the virus is dormant, and such cells are therefore not attacked by the immune system or by standard antiretroviral therapy. To eradicate the virus from the human body and truly cure a patient, reservoirs of latently infected cells need to be activated and elim... Read More

Safer, with more benefits: Parents' vaccine views shifting

ANN ARBOR, Mich. -- Over the same time period that multiple outbreaks of measles and whooping cough made headlines around the country, parents' views on vaccines became more favorable, according to a new nationally-representative poll. Read More

Unknown environmental Contaminant on blood agar plate streaked with S. pyogenes

A streak plate of Strep pyogenes on blood agar, stock culture used for class, was kept at room temp for 1 month. Before disposal a contaminant, presumably environmental, was seen on the plate. The pigment was opaque tan/yellow and with a mucoid surface. Lobate marigins with raised irregular-rh... Read More

Bacterial melanin can replace Non-steroidal anti-inflammatory drugs (NSAIDs) in arthritis treatments

Melanin produced by a marine bacteria Bacillus spp. has shown shown to have good anti-inflammatory activity. The pigment had shown to inhibit inflammatory enzymes cycloxygenase, lipooxygenase, myeloperoxide,NO synthase in vitro at a concentration which was non-cytotoxic..This will be a breakthro... Read More

Improved survival of HIV patients facilitates heart disease research

WASHINGTON (July 27, 2015) - The improved survival rate of HIV patients in sub-Saharan Africa due to effective treatment programs is increasing the ability of researchers in Africa to study the impacts of cardiovascular disease in HIV patients, according to a guest editor page published today in... Read More

TWiP 85 letters

 


Jan writes:


Dear Sirs


This is fun, and although I'm sure someone will gripe about Dicksons enthusiastic response to the crayfish, it made my life easier. I think it's Paragonimus kellicoti. As for eating raw crayfish; how drunk... Read More

Biologist investigates how gene-swapping bacteria evade antibiotics

A scientific peek into bacteria boudoirs is revealing how "sex" among disease-causing microbes can lead different species or strains to become resistant to antibiotic medications. Read More

Cells in Senescence State May Help Slow down Aging and Cancer Treatment

BOC Sciences-Senescence means a state where cells stop further development in their function but clean themselves and remove the extra substance. Scientists found that when cells go into this stage, the growth rate of tumor would slow down, which is true of aging. The finding was made on the lev... Read More

BacterioFiles Special - ASM2015

Here's my summary of ASM2015, an exciting weekend full of science.


(11.5 MB, 12.5 minutes)


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Download Episode<... Read More

A Candida Fourth of July

Candida species on a Candida CHROMagar plate wishes you a happy and safe Fourth of July!
Author: Xiao Hui Lau Read More

Bacillus/Diplobacillus

Simple stain done on an unknown bacteria, showing feathery rhizoid growth on TSA after a 48 hr incubation at 37 degree’s C, isolated from a floor swab. Single bacillus and diplobacillus can be seen though out. Read More

Smut, but the Safe For Work Kind, unless you work with plants....

So I told ccondayan I would post something lewd to MicrobeWorld (who probably thought I was joking). And what could be more lewd than genuine smut? Of course, since this is MicrobeWorld, I'm posting about the group of fungal plant pathogens referred to as smut. When I worked in a plant pathol... Read More

Malaria's key to the liver uncovered

Scientists uncover a port of liver entry for malaria parasites in a report published in The Journal of Experimental Medicine. If these results hold up in humans, drugs that target this entry protein might help prevent the spread of disease. Read More

Shoe Swab

Unknown organism isolated from a swab taken off the bottom of a shoe. Students were asked to swab something in the classroom. One swab was done on the bottom of a shoe and incubated on a TSA plate for 48 hrs at 37 degree’s C. The organism was difficult to scrape so a small chunk of the organis... Read More

Acid Fast Stain#2

Acid Fast stain done on a mix of Staphylococcus aureus and Mycobacterium smegmatis. The stain was done on a culture of M. smegmatis that was incubated on a TSA slant with 1ml TSB added at 37 degree's C for 4 days, S. aureus was incubated in TSB at 37 degree's C for 24 hrs. Several loops of eac... Read More

TWiV 320: Retroviruses and cranberries

Vincent speaks with John Coffin about his career studying retroviruses, including working with Howard Temin, endogenous retroviruses, XMRV, chronic fatigue syndrome and prostate cancer, HIV/AIDS, and his interest in growing cranberries.


Host:  Read More

How long have primates been infected with viruses related to HIV?

Disease-causing viruses engage their hosts in ongoing arms races: positive selection for antiviral genes increases host fitness and survival, and viruses in turn select for mutations that counteract the antiviral host factors. Studying such adaptive mutations can provide insights into the distan... Read More

Some vaccines support evolution of more-virulent viruses

Scientific experiments with the herpesvirus such as the one that causes Marek's disease in poultry have confirmed, for the first time, the highly controversial theory that some vaccines could allow more-virulent versions of a virus to survive, putting unvaccinated individuals at greater risk of ... Read More

Swarming Motility of Pseudomonas aeruginosa

Strain: Pseudomonas aeruginosa PA14
Medium: M8 minimal medium agar plates
Incubation Conditions: 48 hours at 37°C
Pseudomonas aeruginosa is a gram-negative, rod-shaped and monoflagellated bacterium that has an incredible nutritional versatility. Swarming motility, a flagellum-dependent behavi... Read More

TWiM 92 Letters

Dave writes:


Laurene Mascola's distinctive voice and laugh has won my heart this month. I found that when TWiM came up for the third time in my playlist the last couple weeks, I kept listening just for a fix. She should be a star.


I'm glad you had a good reaso... Read More

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