What happens to us after we die? A decomposing corpse becomes its own mini-ecosystem, hosting insects, scavengers and multitudes of microbes. Microbes from the environment, the corpse, as well as the insects and scavengers are blended together and work to recycle tissues back to t... Read More
The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.
Image: Bright-field (top) and fluorescent (bottom) images of zebrafish embryos infected with E. coli strain F11. E... Read More
This episode: Bacterial spores can survive atmospheric entry on an artificial meteorite!
(10.7 MB, 11.25 minutes)
Michael and Vincent present Spotlights, brief reviews of classic papers in the Journal of Bacteriology, and explain how a single bacterial species can reverse autism-like social deficits in the offspring of obese mice.
The TWiP trio visit the Bronx Zoo where Paul solves the case of the Four Year Old with Pulmonary Edema, and talks about his career as the Chief Veterinarian and Director of the Zoological Health program for the Wildlife Conservation Society.
Hosts: Read More
This episode: Feeding mice high-fiber diets reduces their risk of allergic airway disease, even across generations!
(12.1 MB, 13.2 minutes)
The TWiM team explores microbes in snowblower vents on the ocean floor, and cleavage of antibody molecules by a Mycoplasma protease.
Image (right): Photograph of the ‘Subway’ snowblower vent on the sea floor at Axial Seamount, Juan de Fuca Ridge. Visible are white ‘snow’ in the vent a... Read More
A eukaryote without a mitochondrion, and using a phage enzyme to eliminate intracellular bacteria are two topics discussed by the TWiMers on this episode.
Image (right): An entry in the ASM Agar Art Contest which bears an uncanny resemblance to one of the TWiM hosts.
Host... Read More
This episode: In mice, high-fat diets affect their gut microbes, which in turn disrupts their circadian cycles and metabolic health!
(8.6 MB, 9.35 minutes)
The arrival in the US of plasmid-mediated resistance to colistin antibiotics, a last line of defense against many gram-negative bacilli, and a quorum sensing system in a eukaryote are topics of this episode hosted by Vincent, Michael, and Michele.
Image (right): Etest used to determin... Read More
This episode: Amoebas in soil gang up on and eat much larger roundworms!
(10.5 MB, 11.3 minutes)
Insight into the biology of rhinovirus C from cryo-electron microscopy, and a novel antibiotic from a commensal bacterium that grows in the human nose, from the doctors of TWiM.
This episode: I converse with Dr. Michael Smout about a liver fluke parasite could help heal chronic wounds more quickly!
(13.4 MB, 14.6 minutes)
This episode: Viruses domesticated by parasitoid wasps have transferred wasp genes to caterpillar victims, allowing them to survive deadly infections from other viruses! This means that Monarch butterflies are effectively naturally Genetically Modified Organisms (GMOs).
(13.8 MB, 15 m... Read More
Daniel and Vincent solve the case of the Truck Driver from India, discuss why parasites resistant to an antimalarial drug are not transmitted by mosquitoes, and introduce Paul who presents a new case study.
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Design of a synchronously lysing bacterium for delivery of anti-tumor molecules in mice, and hopanoids, the lipids that live forever, brought to you by the four Microbies of TWiM.