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TWiV 425: All picornaviruses, all the time

The TWiVaniellos discuss a thermostable poliovirus empty capsid vaccine, and two cell genes that act as a switch between entry and clearance of picornavirus infection.


Hosts: Vincent Racaniel... Read More

TWiM #142: A membrane-thickness caliper

Vincent, Elio and Michele wind up a year of microbial podcasts with a story about the lack of resistance to a crop antifungal compound, and how a bacterium uses a molecular caliper to measure membrane thickness.


Hosts:  Read More

TWiM #144: Did eukaryotes invent anything?

The TWiMers discuss how changes in domestic laundering affect the removal of microorganisms, and assembly of a nucleus-like structure during viral replication in bacteria.


Hosts: Vincent Racaniello, Read More

Microbes Found on New York City ATM Keypads Mostly from Human Skin, Food

Mapping and identifying all the microbes across New York City is no small feat. Just ask Jane Carlton. About three years ago, Carlton, director of the Center for Genomics and Systems Biology, and professor of biology, at New York University and colleagues won an NYU grand challenge grant for the... Read More

War and peace in the human gut: Probing the microbiome

Human well being often flourishes under conditions of cooperation with others and flounders during periods of external conflict and strife.

According to Athena Aktipis, a researcher at Arizona State University's Biodesign Institute, microbes within the body--collectively known as the microbi... Read More

Green Monkeys Acquired Staphylococcus aureus From Humans

Washington, DC – July 29, 2016 - Many deadly diseases that afflict humans were originally acquired through contact with animals. New research published in ASM’s Applied and Environmental Microbiology shows that pathogens can also jump the species barrier to move from humans to animals. The study... Read More

Will the flu kill you? It may depend on your birth year

Your birth year predicts—to a certain extent—how likely you are to get seriously ill or die in an outbreak of an animal-origin influenza virus, new research suggests.

Until now, scientists thought that previous exposure to a flu virus conferred little or no immunological protection against ne... Read More

Skin bacterium releases enzyme that may protect against damage and disease

The study - from Lund University in Sweden and published in the journal Scientific Reports - investigates a skin bacterium called Propionibacterium acnes. Senior author Dr. Rolf Lood, from Lund's Department of Clinical Sciences, explains:

"The name originates from the fact that the bacterium ... Read More

Mechanism of Probiotic Health Promotion Revealed

Washington, DC – December 2, 2016 – In several clinical trials, the probiotic bacterium Lactobacillus paracasei DG has been shown to promote health, but until now, the mechanism has remained a black box. New research now suggests that the health benefits arise from communication between the prob... Read More

Diagnostic guidelines for bloodstream infections aim to shorten time to accurate therapy

One of the most dangerous places for an infection to occur is in the bloodstream. Septicemia, when microbes are present in the blood, not only allows bacteria access to other internal organs through the highway of our circulatory system, but also can cause a massive inflammatory response, leadin... Read More

Treatment for chronic hepatitis B linked to increased rates of colorectal and cervical cancer

April 15, 2016, Barcelona, Spain: A new study presented today demonstrates a potential link between treatment of long-term oral nucleos(t)ide analogues and an increased risk of colorectal (p=0.029) and cervical (p=0.049) cancer in patients with chronic Hepatitis B virus (HBV). The study results ... Read More

An achilles heel for Clostridium difficile infections?

Clostridium difficile is a dangerous superbug. Infections with this bacterium can cause life-threatening diarrhea, and they are most likely to affect the elderly or people with health problems who spend a lot of time in hospitals (where C. difficile flourishes). The Centers for Disease Control a... Read More

Zika virus plaque assay

Several weeks ago we perfected a plaque assay for Zika virus, based on our existing assays for enteroviruses. Shown is a photograph of two plates stained with crystal virolet with clearly delineated plaques. The cells are Vero and the Zika virus strain is MR766, an African isolate. Anyone intere... Read More

BacterioFiles 273 - Bottle-Biting Bacteria

This episode: Newly discovered bacteria can break down especially long-lived type of plastic!


(6.4 MB, 7 minutes)


Show notes: 




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Ferreting out an improved Ebola animal model

We’ve previously covered the importance of diagnostics in disease control and treatment. This is vital to controlling disease progression and transmission, but epidemiology studies can’t always show how a disease progresses or transmits. This is where scientists need a well-characterized animal ... Read More

UMMS scientists use CRISPR to discover Zika and dengue weaknesses

Scientists at the University of Massachusetts Medical School (UMMS) have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication. This work, led by Abraham Brass, MD, PhD, assistant professor in microbiology & physiological systems, reveals new lea... Read More

Student Thoughts On The First Day of Microbiology Class

I teach Microbiology at the University of Puget Sound every fall semester. The swiftly changing field of microbiology has depth and breath...and I was interested to learn what my students thought of the topic at the beginning of the first day of class. We will revisit this subject at the end o... Read More

Gut microbes may play a role in Parkinson's disease

Many people with Parkinson’s disease also experience digestive symptoms (like constipation) for some time before their diagnosis. But until recently, research on the degenerative disease and how to treat it has focused on understanding how Parkinson’s works in the brain.

In a new study out th... Read More

Wealth of unsuspected new microbes expands tree of life

Researchers at the University of California, Berkeley, who have discovered more than 1,000 new types of bacteria and Archaea over the past 15 years lurking in Earth's nooks and crannies, have dramatically rejiggered the tree to account for these microscopic new life forms. Read More

Virus Watch: Zika Edition

Virus Watch is a new weekly video series that explores the amazing world of viruses. This week: the latest research on Zika virus, including finding virus in Brazilian monkeys, dengue antibodies helping Zika virus infection, and brain organoids to study how Zika virus causes microcephaly. Read More
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