Researchers working in the UK and The Gambia, have developed a new approach to the diagnosis of tuberculosis (TB) that relies on direct sequencing of DNA extracted from sputum (a technique called metagenomics) to detect and characterize the bacteria that cause TB without the need for time-consum... Read More
As is our custom at this time of year, we go over the material that has appeared in this blog over the last six months. Seems like a lot of stuff, but it’s the result of the work of quite a number of dedicated people, all of whom deserve our gratitude.
Click "source" to read more. Read More
Desperate for breast milk, some new mothers who can't nurse their babies are turning to online sources, typically strangers with ample supplies. But a new study finds that human milk bought and sold on the Internet may be contaminated — and dangerous.
Nearly 75 percent of breast milk bought t... Read More
The Amazon river is the largest river in the world. It drains the entire Amazon rainforest, sending leftover nutrients, detritus, and minerals from the South American jungle out into the tropical Atlantic ocean. This runoff forms a freshwater plume, hundreds of miles across, that profoundly affe... Read More
Oman's first MERS coronavirus patient died in hospital on Sunday from lung failure, state news agency ONA said.
The Middle East Respiratory Syndrome Coronavirus (MERS-CoV), which can cause coughing, fever and pneumonia, emerged in Saudi Arabia last year and has been reported in Qatar, France,... Read More
The active ingredient in vinegar, acetic acid, can effectively kill mycobacteria, even highly drug-resistant Mycobacterium tuberculosis, an international team of researchers from Venezuela, France, and the US reports in mBio®, the online open-access journal of the American Society for Microbiolo... Read More
New research published in the online journal PLoS Outbreaks predicts new Ebola cases could reach 6,800 in West Africa by the end of the month if new control measures are not enacted.
Arizona State University and Harvard University researchers also discovered through modelling analysis that th... Read More
Viruses are the most abundant biological entities on the planet with approximately 1030 in the world’s oceans at any time. As such, they play a central role in global nutrient cycling. Despite their ecological importance, little is known about how viruses interact with their hosts due to the dif... Read More
A still somewhat unfamiliar term is floating around: the pan-genome. In 2005, Tettelin et al. coined the term along with genome analyses of eight Streptococcus agalactiae strains, and Merry introduced it to this blog, some time back already. Today, a keyword search in PubMed returns roughly 200 ... Read More
In 2011, while construction workers were digging a foundation at a site in Queens, New York, their equipment struck against something metal. Then a body rolled out of the rubble. Thinking that they might have unearthed the shallow grave of a murder victim, the workers immediately called the New ... Read More
The journal Zentralblatt für Bakteriologie, Parasitenkunde u. Infektionskrankheiten was one of the leading publication in the early days of Microbiology. Many of the great discoveries of microbial pathogens were published therein. An example is the 1898 Japanese microbiologist Kiyoshi Shiga acco... Read More
Methane-producing microbes may be responsible for the largest mass extinction in Earth’s history.
Evidence left at the crime scene is abundant and global: Fossil remains show that sometime around 252 million years ago, about 90 percent of all species on Earth were suddenly wiped out — by far ... Read More
Single-cell genomics could provide new insight into the biology of malaria parasites (including their virulence and levels of drug resistance) to ultimately improve treatment and control of the disease, according to new research funded by the Wellcome Trust and the National Institutes of Health.... Read More
A single dose of an investigational influenza drug was able to reduce the duration of fever and viral shedding, researchers said here.
In a combined analysis of two randomized placebo-controlled trials, the neuraminidase inhibitor peramivir (Rapivab), given by injection within 48 hours of sym... Read More
Johns Hopkins researchers have found evidence in mice that a tuberculosis (TB) infection in the lungs triggers immune system signaling to the gut that temporarily decreases the diversity of bacteria in that part of the digestive tract.
The Johns Hopkins researchers showed that this decrease i... Read More
Gut bacteria in premature infants don't come from their mothers, but from microbes in the neonatal intensive-care unit (NICU), a new study finds. Babies typically get their gut bacteria from their mothers during childbirth. Premature infants, however, receive antibiotics during their first week ... Read More
A team of scientists has reconstructed how bacteria tightly control their growth and division, the cell cycle, by destroying specific proteins through regulated protein degradation. All organisms use controlled protein degradation to alter cell behavior in response to changing environment. A pro... Read More
An international team of scientists from Singapore, Thailand, China and Australia has cracked the genetic code of the liver fluke parasite, Opisthorchis viverrini, using a unique DNA analysis technique developed at A*STAR’s Genome Institute of Singapore (GIS).
GIS’s DNA analysis technique ha... Read More
Pathogenic fungi like Candida albicans can cause oral, skin, nail and genital infections. While exposure to pathogenic fungi is generally not life-threatening, it can be deadly to immunocompromised patients with AIDS or cancer. A variety of antifungal medications, such as triazoles and polyenes,... Read More
There's a belief that says exposing people -- especially babies and young children -- to different kinds of germs early in life can keep them from developing illnesses like asthma, allergies, and other diseases that affect the immune system. The theory, called the “hygiene hypothesis,” is that o... Read More