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Paper device spots antibiotic-resistant bacteria

Scientists in Canada have developed a paper-based device that checks if bacteria are resistant to certain antibiotics. The simple system could help users in remote areas pick the most appropriate treatment for bacterial infections.

Click on 'source' to read more Read More

TWiM 89 Letters

Peter writes:


Dear Michele,


Prof. Szybalski might have been referring to a truck with a wood gas generator


Apparently they are still in use north of the b... Read More

Ancient whodunit may be solved: The microbes did it!

Methane-producing microbes may be responsible for the largest mass extinction in Earth’s history.

Evidence left at the crime scene is abundant and global: Fossil remains show that sometime around 252 million years ago, about 90 percent of all species on Earth were suddenly wiped out — by far ... Read More

Pictures Considered #10. The Origin of Pulsed-Field Gel Electrophoresis

In May 1984, readers of an article by Schwartz and Cantor in the prestigious journal Cell were to stumble upon pictures of DNA agarose gels that were among the lousiest of such ever published after the method was introduced in the early 70s. Why did the editors of Cell risk their reputation? Or ... Read More

Influenza A potentiates pneumococcal co-infection: New details emerge

Influenza infection can enhance the ability of the bacterium Streptococcus pneumoniae to cause ear and throat infections, according to research published ahead of print in the journal Infection and Immunity.

In the study, the investigators infected mice with either influenza alone, pneumococc... Read More

Bacterial defense policies

High-resolution cryo-electron microscopy has now revealed in unprecedented detail the structural changes in the bacterial ribosome which results in resistance to the antibiotic erythromycin.

Click "source" to read more. Read More

Oral Bacteria and Cancer

Over a number of years, epidemiological studies established several well-defined risk factors for cancer, including age, heredity, diet, tobacco use, chronic viral infections, and inflammation. Paradoxically, the success of these studies left little room for incorporation of any new factors or c... Read More

ASM GM 2014 - Bacteria in Urine Could Cause Overactive Bladder

Contrary to popular belief, urine is not sterile and the bacteria in it may be associated with overactive bladder (OAB) in some women. Presenters will discuss their research ... Read More

Chromosome Organization the Pseudomonas Way, Part 1

(Re-)Introducing the Pseudomonads. Despite the somewhat murky provenance of their name, pseudomonads are everything but "pseudo-" in terms of their metabolic versatility: they are bacterial omnivores, heterotrophs yet far from picky. Members of the family Pseudomonadaceae (Gammaproteobacteria) a... Read More

Innocence by Viral Tagging - Finalist in Ocean 180 Video Challenge

Viruses are the most abundant biological entities on the planet with approximately 1030 in the world’s oceans at any time. As such, they play a central role in global nutrient cycling. Despite their ecological importance, little is known about how viruses interact with their hosts due to the dif... Read More

New Insights on an Ancient Plague Could Improve Treatments for Infections

Dangerous new pathogens such as the Ebola virus invoke scary scenarios of deadly epidemics, but even ancient scourges such as the bubonic plague are still providing researchers with new insights on how the body responds to infections.

In a study published online Sept. 18, 2014, in the journal... Read More

How a microscopic team alters the course of carbon in the Atlantic ocean - Finalist in Ocean 180 Video Challenge

The Amazon river is the largest river in the world. It drains the entire Amazon rainforest, sending leftover nutrients, detritus, and minerals from the South American jungle out into the tropical Atlantic ocean. This runoff forms a freshwater plume, hundreds of miles across, that profoundly affe... Read More

Community-based HIV prevention can boost testing, help reduce new infections

Communities in Africa and Thailand that worked together on HIV-prevention efforts saw not only a rise in HIV screening but a drop in new infections, according to a new study in the peer-reviewed journal The Lancet Global Health.

The U.S. National Institute of Mental Health's Project Accept —... Read More

Researchers Unlock the Genetic Code of Cancer-Causing Liver Fluke Parasite

An international team of scientists from Singapore, Thailand, China and Australia has cracked the genetic code of the liver fluke parasite, Opisthorchis viverrini, using a unique DNA analysis technique developed at A*STAR’s Genome Institute of Singapore (GIS).

GIS’s DNA analysis technique ha... Read More

8 unusual uses for probiotics

Most of us are familiar with taking our daily probiotic supplement in the conventional way, either in capsule or powder form. It is however becoming increasingly apparent that people are discovering some weird and wonderful ways to use their probiotics, and here nutritional therapist Jo Saunders... Read More

Cationic small molecules hold great potential for preventing and treating fungal infections

Pathogenic fungi like Candida albicans can cause oral, skin, nail and genital infections. While exposure to pathogenic fungi is generally not life-threatening, it can be deadly to immunocompromised patients with AIDS or cancer. A variety of antifungal medications, such as triazoles and polyenes,... Read More

'Transformer' protein provides new insights into Ebola virus disease

A new study reveals that a protein of the Ebola virus can transform into three distinct shapes, each with a separate function that is critical to the virus's survival. Each shape offers a potential target for developing drugs against Ebola virus disease, a hemorrhagic fever that kills up to 9 ou... Read More

Laser tool speeds up detection of Salmonella in food products

Purdue University researchers have developed a laser sensor that can identify Salmonella bacteria grown from food samples about three times faster than conventional detection methods.

Known as BARDOT (pronounced bar-DOH'), the machine scans bacteria colonies and generates a distinct black and... Read More

Retrospective, June 2014 - Small Things Considered

As is our custom at this time of year, we go over the material that has appeared in this blog over the last six months. Seems like a lot of stuff, but it’s the result of the work of quite a number of dedicated people, all of whom deserve our gratitude.

Click "source" to read more. Read More

Terms of Biology: The Pan-Genome

A still somewhat unfamiliar term is floating around: the pan-genome. In 2005, Tettelin et al. coined the term along with genome analyses of eight Streptococcus agalactiae strains, and Merry introduced it to this blog, some time back already. Today, a keyword search in PubMed returns roughly 200 ... Read More

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