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MWV Episode 94 - TWiM #99: Careers in Biodefense
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Think We're Rid of Measles? Think Again

Over the last few weeks, the numerous outbreaks of measles in Canada have led many public health officials and microbiologists to shake their collective heads. The reason is simple: this should not be happening. Of all the pathogenic viruses, this one has been on our radar for nearly 200 years a... Read More

Superbugs should scare you more than Ebola in US

The first case of Ebola in the United States was announced today, with a patient in Dallas who traveled to the US from Liberia. The resultant hysteria and xenophobia prompts this reminder. There is NO need to panic.

Ebola is NOT transmitted before a patient develops symptoms. Ebola is transmi... Read More

Small Loop in Human Prion Protein Prevents Chronic Wasting Disease

Chronic wasting disease (CWD) — an infectious disease caused by prions — affects North American elk and deer, but has not been observed in humans. Using a mouse model that expresses an altered form of the normal human prion protein, researchers at University of California, San Diego School of Me... Read More

The pathogen detectives: sourcing the post-earthquake cholera outbreak in Haiti

Natural disasters such as earthquakes can have far-reaching effects beyond the damage caused on the day they occur. The 2010 earthquake in Haiti damaged the already limited sanitation systems leading to areas without adequate toilet and washing facilities; perfect for the spread of infection dis... Read More

Antibodies discovery could lead to universal dengue vaccine

A major new class of antibodies that can make the four different types of dengue virus (DENV) non-infectious has been discovered by a group of international researchers, including from the University of Melbourne.

The discovery could lead to the development of better vaccines and laboratory t... Read More

Virus kills triple negative breast cancer cells, tumor cells in mice

A virus not known to cause disease kills triple-negative breast cancer cells and killed tumors grown from these cells in mice, according to Penn State College of Medicine researchers. Understanding how the virus kills cancer may lead to new treatments for breast cancer.

Adeno-associated virus... Read More

Nibbled to Death: U.Va. Researchers Discover New Way Human Cells Are Killed

Researchers at the University of Virginia School of Medicine studying a potentially deadly parasitic infection have discovered a previously unknown way that human cells are killed, with the parasitic amoeba essentially nibbling cells to death – as a piranha might attack its prey.

Until now, r... Read More

Muddled about MERS? Here’s A Quick Guide

While I was working on the “H1N-What?” post, I also knew there would soon be questions about MERS (Middle East Respiratory Syndrome), just as there were about SARS. So here are the essentials of what we know and don’t know about MERS—which has just been reported in the U.S.—as well as intriguing... Read More

Ebola virus: Genes 'play significant role in survival'

Genetic factors could play an important role in whether people survive the Ebola virus, say US scientists.

A study of mice infected with the virus found they showed a number of different symptoms, with 19% remaining unaffected by the disease.

This could explain why some people recover from... Read More

Who Made That Flavor? Maybe A Genetically Altered Microbe

For practically our whole history of cooking and eating, we've gotten our spices and most flavors (not to mention all of the other basic nutrients that keep us alive) straight from plants.

But researchers and biotech companies are starting to produce some of these nutrients and flavors — espe... Read More

State's Flu Shot Rule for Preschoolers Helped

A Connecticut law requiring flu shots for children entering preschool or daycare has reduced flu-related hospitalizations of young children by 12 percent, according to a new study. The jump in flu vaccinations of young children -- to 84 percent in 2012-2013 from about 68 percent in 2009-2010 -- ... Read More

Over 900 Hookworm Genes "turn on" to wreak havoc

Tiny parasitic hookworms infect nearly half a billion people worldwide, almost exclusively in developing countries. Researchers say sequencing the genome of a particular species could help develop more effective drugs.

Other hookworm species cause more disease among humans, but Ancylostoma ce... Read More

Deadly bacteria release sparks concern at Louisiana lab

A dangerous, often deadly, type of bacteria that lives in soil and water has been released from a high-security laboratory at the Tulane National Primate Research Center in Louisiana. Officials say there is no risk to the public. Yet despite weeks of investigation by multiple federal and state a... Read More

A Faster Way to Diagnose Antibiotic Resistance

Novel test could slash wait time and curb inappropriate prescriptions.

Antibiotic resistance, which transforms ordinary microbes into menaces that cannot be easily controlled, is exacting a growing toll on the human population. More than two million people in the U.S. develop drug-resistant i... Read More

Scientists discover how a killer fungus attacks HIV patients

Researchers have discovered that a type of white blood cell carries a deadly fungus into the brains of HIV positive patients, causing meningitis which kills more than 600,000 people a year. The discovery could lead to more effective ways of tackling the deadly fungus as it infects the human body... Read More

Progress in the fight against harmful fungi

A group of researchers at the Max F. Perutz Laboratories has created one of the three world's largest gene libraries for the Candida glabrata yeast, which is harmful to humans. Molecular analysis of the Candida glabrata fungus mutations led to the discovery of 28 new genes that are partly respon... Read More

Ultra-violet Light Works as Screening Tool for Bats with White-nose Syndrome

Scientists working to understand the devastating bat disease known as white-nose syndrome (WNS) now have a new, non-lethal tool to identify bats with WNS lesions —ultraviolet, or UV, light.

If long-wave UV light is directed at the wings of bats with white-nose syndrome, it produces a distinct... Read More

Pathogens in Cheese – Researchers Follow the Traces of Deadly Bacteria

If food products are not produced in a hygienic environment, consumers can face the threat of dangerous pathogens. This is exactly what happened in 2009 and 2010 when two different strains of Listeria monocytogenes were found in the traditional Austrian curd cheese known as “Quargel”. 34 people ... Read More

Nutrient-absorbing surface’s assembly revealed: study

Vanderbilt University researchers have now discovered how intestinal cells build this specialized structure, which is critical for absorbing nutrients and defending against pathogens. The findings, published April 10 in the journal Cell, reveal a role for adhesion molecules in brush border assem... Read More

Brewing yeasts reveal secrets of chromosomal warfare and dysfunction

Using two yeasts that have been used to brew tea and beer for centuries, researchers at Fred Hutchinson Cancer Research Center have revealed how reproductive barriers might rapidly arise to create species boundaries. Schizosaccharomyces pombe has been used to brew beer in Africa, whereas its clo... Read More
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