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A virus that melts sea stars

Sea stars are lovely marine invertebrates with a round central body connected to multiple radiating legs (photo credit). In the past year millions of sea stars in the west coast waters of North America have melted into piles of slime and ossicles. Sea star associated densovirus might be the caus... Read More

TWiP 79: Across the river and into the trees

Vincent and Dickson discuss the spread of P. knowlesi in Malaysia, and how Leishmania parasites protect the sandfly gut from bacterial infection.


Hosts: Vincent Racaniello and&nbs... Read More

TWiP 79 letters


Jesse writes:


Doctors TWiP,


I came across this paper and thought it sounded interesting for a discussion on TWiP:


Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection
Read More

Pseudomonas aeruginosa with black extracellular pigment

Pseudomonas aeruginosa isolated from sputum into department of Microbiology - Riuniti Hospital Reggio Calabria .
This strain of Pseudomonas secretes brown/black extracellular pigment: pyomelanin.
Photo from D'Aleo Francesco archive. Read More

Alternaria change DTM agar colour

Alternaria and other demaziacee normally not change the DTM agar plates colour. This Alternaria isolated into Mycology Laboratory in Policlinic "G. Martino" - University of Messina, change the color on DTM agar. Read More

Nocardia asteroides on Gram stain

Presence of Gram-positive, partially acid-fast rods, which have grown in branching chains resembling fungal hyphae. (Gram stain; original magnification, ×100). Image courtesy MicrobeWorld user Kyriakos Zaragkoulias, Specialty Registrar (StR) in Medical Microbiology at General Hospital of Thessal... Read More

VIBRIO CHOLERAE O1 ISOLATEDFROM HUMAN STOOL

THIS IS VIBRIO CHOLERAE O1 OGAWA ISOLATED FROM HUMAN STOOL SWAB PLATED ON BILE SALT AGAR Read More

An Ebola virus protein can cause massive inflammation and leaky blood vessels

Ebola GP protein covers the virus' surface and is shed from infected cells during infection. Shed GP can trigger massive dysregulation of the immune response and affect the permeability of blood vessels.

Click 'source" to read more. Read More

New study reveals why some people may be immune to HIV-1

Natural genetic variation in a protective antiviral enzyme holds promise for new therapies.

Doctors have long been mystified as to why HIV-1 rapidly sickens some individuals, while in others the virus has difficulties gaining a foothold. Now, a study of genetic variation in HIV-1 and in the c... Read More

Flu virus key machine: First complete view of structure revealed

Scientists looking to understand – and potentially thwart – the influenza virus now have a much more encompassing view, thanks to the first complete structure of one of the flu virus’ key machines. Knowing the structure allows researchers to finally understand how the machine works as a whole, a... Read More

Worse Than The Bite

City dwellers across the U.S. might agree on one common enemy: bedbugs. But hey, not to worry, right? "Bedbugs are not known to spread diseases, but bites can be very itchy and irritating." Or so says the New York City Department of Health. But that assertion may not be true. Because a new study... Read More

Why CRISPR Doesn't Work in E. coli

We received this query:

»I enjoyed the article on your blog 'Six Questions About CRISPRs' by Merry Youle. I am an ex-lambdologist, having quit phage lambda in the early 70s and moved to GM-plants. There is one thing about CRISPR that I do not understand: Why did lambdologists not find CRISPR?... Read More

Pink-pigmented Pseudomonas Aeruginosa

A pink-pigmented strain of Pseudomonas aeruginosa is shown in the picture. This was photographed in University of Colorado Hospital's clinical lab by the microbiology department. The organism is shown on Mueller-Hinton agar for Kirby-Bauer sensitivity testing.

The pigment pyorubin is responsi... Read More

3D printing brings new feel to microbes

UK bioscience funders BBSRC and scientists from Oxford Brookes University teamed-up to run Giant Germs – an event tailored specifically to the blind and visually impaired. The day allowed visitors to discover the microscopic world of microbes for the very first time thanks to 3D printing technol... Read More

Slime producing Staphylococcus epidermidis on Congo Red agar

Slime production by Staphylococcus epidermidis on Congo Red agar; demonstrated by black colored colonies. Slime production is one of the most important virulence factors produced by Coagulase negative Staphylococci.

The colonies of slime non-producing strains remain pink to red.
Read More

New Tools in Fight Against Virus that Attacks the Brain

Researchers have developed new insight into a rare but deadly brain infection, called progressive multifocal leukoencephalopathy (PML). This disease – which is caused by the JC virus – is most frequently found in people with suppressed immune systems and, until now, scientists have had no effect... Read More

UCI team develops test to rapidly diagnose bloodstream infection

New technology can detect bacterial invaders with unprecedented speed, sensitivity.

A new bloodstream infection test created by UC Irvine researchers can speed up diagnosis times with unprecedented accuracy, allowing physicians to treat patients with potentially deadly ailments more promptly... Read More

Virus devastating sea stars on Pacific Coast identified

Scientists have now explained the mysteriously sudden appearance of a disease that has decimated sea stars on the North American Pacific Coast.

In a paper published Monday, November 17, 2014 in the journal Proceedings of the National Academy of Sciences, Cornell University microbiologist Ian ... Read More

Scripps Research Institute Scientists Reveal Weak Spots in Ebola’s Defenses

New Study Exposes How ZMapp Therapy Attacks Virus and Suggests Strategies to Improve It.

Scientists at The Scripps Research Institute (TSRI) have identified weak spots on the surface of Ebola virus that are targeted by the antibodies in ZMapp, the experimental drug cocktail administered to se... Read More

Study Shows Bed Bugs Can Transmit Parasite that Causes Chagas Disease

The bed bug may be just as dangerous as its sinister cousin, the triatomine, or “kissing” bug. A new study from Penn Medicine researchers in the Center for Clinical Epidemiology and Biostatistics demonstrated that bed bugs, like the triatomines, can transmit Trypanosoma cruzi, the parasite that ... Read More
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