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TWiM 57 Letters

Wink writes:


Great HAI work! I'm not through it yet. I want to question, though, whether fomites are really important in influenza transmission. I don't think so.
Wink Weinberg (ID)


[flu can transmit by fomites in guinea pigs: Read More

Salmonella uses protective switch during infection

For the first time, researchers have found a particular kind of molecular switch in the food poisoning bacteria Salmonella Typhimurium under infection-like conditions. This switch, using a process called S-thiolation, appears to be used by the bacteria to respond to changes in the environment du... Read More

Biology Plug N' Play

When you're hard drive fails, you order a new one online and then swap it out. Why can't we do that for biological parts as well? From DNA robots and "organs-on-a-chip" to nanobristles that grab-and-release drugs, this slideshow explores the two major goals of synthetic biology: to build new bio... Read More

Food Laboratory Accuracy Remains A Concern

Food microbiology laboratories continue to submit false negative results and false positive results on a routine basis. A retrospective study of nearly 40,000 proficiency test results over the past 14 years, presented today at the 113th General Meeting of the American Society for Microbiology, ... Read More

Bacteria may provide some of gastric bypass surgery's boost

In the latest of a slew of studies examining the role of the so-called microbiome -- the mix of microscopic critters that colonize our bodies and our environment -- in human health, Harvard researchers said Wednesday that part of the reason that Roux-en-Y gastric bypass surgery works so well in ... Read More

Max Perutz 1914-2002: 'the godfather of molecular biology' - video

Scientists who worked with the Nobel prize-winning pioneer discuss his legacy alongside footage and previously unseen interviews. Max Perutz, the Austrian-born British molecular biologist, founded the MRC Laboratory of Molecular Biology (LMB) at Cambridge University in the postwar years where he... Read More

'Dark matter' of life: Mysterious bacteria sequenced

The genome of mysterious bacteria that lurk in hospital drains has been sequenced.

Low levels of the bacteria, known only as candidate phylum TM6, have been found in water systems around the world, yet because they could not be cultured in the lab, almost nothing was known about them.

The ... Read More

A single amino acid change switches avian influenza H5N1 and H7N9 viruses to human receptors

Two back-to-back papers were published last week that provide a detailed analysis of what it would take for avian influenza H5N1 and H7N9 viruses to switch to human receptors. A single amino acid change in the viral hemagglutinin protein is sufficient to quantitatively change binding of the viru... Read More

HIV and ‘hot spring’ virus hijack same protein

There’s a surprising connection between HIV, Ebola, and viruses that infect organisms called archaea that grow in volcanic hot springs.

The viruses hijack the same set of proteins to break out of infected cells, new research shows.

In eukaryotes—the group that includes plants and animals—a... Read More

AIDS Epidemic: Is an End Possible?

More than 30 years after the discovery of the AIDS virus, experts are optimistic that a cure for the disease will be found, and that an end to the AIDS epidemic is possible.

But they caution there is still a lot of work to be done.

Since the first cases of AIDS were reported in 1981, more ... Read More

A potential new target to thwart antibiotic resistance

Viruses in gut confer antibiotic resistance to bacteria. Bacteria in the gut that are under attack by antibiotics have allies no one had anticipated, a team of Wyss Institute scientists has found. Gut viruses that usually commandeer the bacteria, it turns out, enable them to survive the antibiot... Read More

Metabolic Model of E. Coli Reveals How Bacterial Growth Responds to Temperature Change

Bioengineers at the University of California, San Diego have developed a computational model of 1,366 genes in E. coli that includes 3D protein structures and has enabled them to compute the temperature sensitivity of the bacterium's proteins. The study, published June 7 in the journal Science, ... Read More

Stinky feet may lead to better malaria traps

For decades, health officials have battled malaria with insecticides, bed nets and drugs. Now, scientists say there might be a potent new tool to fight the deadly mosquito-borne disease: the stench of human feet.

In a laboratory study, researchers found that mosquitoes infected with the tropi... Read More

New visualization reveals virus particles have more individuality than thought

Virus particles of the same type had been thought to have identical structures, like a mass-produced toy, but a new visualization technique developed by a Purdue University researcher revealed otherwise.

Wen Jiang, an associate professor of biological sciences, found that an important viral s... Read More

Polio Virus Discovered in Sewage From Israel

The Polio virus has been found in a sewage sample from Israel for the first time since 2002, the World Health Organization announced on Monday. But no children or adults newly paralyzed by polio have been identified in Israel or in Gaza or the West Bank.

The sample was from Rahat, a city in t... Read More

TWiV 235: Live in Edmonton, eh?



Hosts: Vincent Racaniello and Rich Condit Read More

Lab Notes: Stop Hepatitis C from Multiplying

Hep C may be thwarted by muting its ability to replicate. Also this week: a promising approach to preserve muscle in ALS, and the body's microbiota fight a sexually-transmitted disease.

Stopping HCV in Its Tracks

Researchers have identified a possible new approach to stopping hepatitis C v... Read More

Honor the best in microbiology by nominating them for an asm2014 award

Recognize an outstanding colleague, student, or mentor by nominating him/her for an asm2014 achievement award. The ASM Awards Program strives to honor the best in research, service, and education, and needs your help to do so! The deadline for awards to be presented at asm2014 is July 1, 2013. P... Read More

Fungus, Bacteria Found In Drugs From Tennessee Pharmacy

The FDA reports finding of bacteria and fungus in drug vials from a Tennessee compound pharmacy that recalled all of its injectable medicines last month. The CDC is evaluating these and other sterile products produced by Main Street Family Pharmacy in Newbern, TN. A fungal meningitis outbreak in... Read More

Novel Coronavirus Particles

Transmission electron micrograph of novel coronavirus particles, colorized in yellow.

Credit: NIAID

http://www.flickr.com/photos/niaid/8618697423/in/photostream/
Read More
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