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How we used to talk about Measles

These days, the happiest place on Earth isn't so cheerful. In December, a large number of people started coming down with measles after visiting Disneyland in California. So far, about 80 measles cases have been reported in the state, an unusually large number for a virus that has long been unde... Read More

Among gut microbes, strains, not just species, matter

A large community of microorganisms calls the human digestive tract home. This dynamic conglomerate of microscopic life forms - the gut microbiome - is vital to how people metabolize various nutrients in their food, how their immune systems react to infection, and how they respond to various med... Read More

Green tea ingredient may target protein to kill oral cancer cells

A compound found in green tea may trigger a cycle that kills oral cancer cells while leaving healthy cells alone, according to Penn State food scientists. The research could lead to treatments for oral cancer, as well as other types of cancer.

Earlier studies had shown that epigallocatechin-3... Read More

How a Bacterial Virus Found in Jerusalem Sewage Could Prevent Root Canal Infections

According to the Review on Antimicrobial Resistance commissioned by the UK Prime Minister, failing to address the growing problem of drug-resistant infections could cause 10 million deaths a year and cost up to $100 trillion USD by 2050.

Now, researchers from the Hebrew University of Jerusal... Read More

BacterioFiles 202 - Controlling Coliform Computers

This episode: Programming bacteria to sense and keep genomic records of environmental inputs!


(15.9 MB, 17.4 minutes)


Show notes: 
Read More

HIV strain matters for treating new cases

The specific strain of HIV that a person first contracts can have a lasting impact on how the virus disrupts his or her immune system, say researchers.

“This may have important implications for cure strategies aimed at eliminating the viral reservoir, as individuals infected with low replicat... Read More

Viral Supercomputer Simulations

Jason Roberts, a virologist at the Victorian Infectious Disease Reference Laboratory in Melbourne, Australia, creates three-dimensional simulations of viruses showing how the molecules that make up the capsid and genome might move in very short periods of time. I visited Jason in his laboratory ... Read More

Paenibacillus glucanolyticus spore

Paenibacillus species have been isolated from a wide variety of sources including soil, water, the plant rhizosphere, plant materials, food, fodder, faeces and diseased insect larvae. They are facultative anaerobes or strict aerobes and mostly motile, endospore forming rods. This is the first ti... Read More

Exophiala dermatitidis

Beatrice Rogolino, BS, M.Sc has isolated from stool this mould into department of Microbiology - Riuniti Hospital Reggio Calabria . Photo of D'Aleo Francesco BS, M.Sc Read More

TWiP 82 letters


Allan writes:


Dear Vincent, Dickson and Daniel,


I like your idea of a TWIP coffee mug prize (or maybe a mug discount).


In this second case study you presented, the present symptoms are pretty vague, but his history is interesting. Also since with ... Read More

Chromobacterium violaceum, Staphylococcus chromogenes, Staphylococcus aureus, Staphylococcus epidermidis

Created by: Michelle Vu, Research Associate, BS Microbiology
Isolate: Chromobacterium violaceum, Staphylococcus epidermidis, Staphylococcus aureus
Media: Blood Agar
Incubation Conditions: 24 hours at 37C + 24 hours at Room Temperature


Pictured is Chromobacterium violaceum, Staphylococcus... Read More

Gut Bacteria Byproduct Linked to Chronic Kidney Disease for the First Time

Cleveland Clinic researchers have, for the first time, linked trimethylamine N-oxide (TMAO) – a gut metabolite formed during the digestion of egg-, red meat- or dairy-derived nutrients choline and carnitine – to chronic kidney disease.

TMAO has been linked to heart disease already, with blood... Read More

Oil Eating Microbes Have Worldwide Underground Connections

Living deep underground ain't easy. In addition to hellish temperatures and pressures, there's not a lot to eat. Which is why oil reservoirs are the microbes’ cornucopia in this hidden realm.

Microbes feast on many oil reservoirs, but it has been unclear how the micro-organisms got to those ... Read More

Virus-cutting enzyme helps bacteria remember a threat

Bacteria may not have brains, but they do have memories, at least when it comes to viruses that attack them. Many bacteria have a molecular immune system which allows these microbes to capture and retain pieces of viral DNA that they have encountered in the past, in order to recognize and destro... Read More

Fun Agar Drawings: Chromobacterium violaceum, Staphylococcus aureus

Isolate: Chromobacterium violaceum, Staphylococcus aureus
Agar: Mueller Hinton Agar
Incubation Conditions: 24 hours at 37C + 24 hours at Room Temperature
Created by: Michelle Vu, Research Associate, BS Microbiology

Pictured is Chromobacterium violaceum and Staphylococcus aureus shaped in a... Read More

TWiV 323: A skid loader full of viromes

Hosts: Vincent RacanielloDickson DespommierAlan Dove, Read More

Mothers can pass traits to offspring through bacteria’s DNA

It’s a firmly established fact straight from Biology 101: Traits such as eye color and height are passed from one generation to the next through the parents’ DNA.

But now, a new study in mice by researchers at Washington University School of Medicine in St. Louis has shown that the DNA of ba... Read More

Fungal close up

Close up image of the edge of an unknown fungal contaminant showing concentric rings of black spore formation (center of colony) and nonspore forming white hypae on the outer edge of the colony. Fungal contaminant was found on TSA after a month of refrigerated temperatures, presumably an air bo... Read More

TWiM 97 Letters


Dennis writes:
hi Doc,


A paper just published in nature:


http://www.nature.com/nature/journal/vaop/ncurrent/pdf/nature14098.pdf


reports an effective antibiot... Read More

Why we haven't eradicated the plague

More than 600 years after the bubonic plague wiped out about half of Europe, scientists still don’t fully understand how bacteria that cause the disease travel from the site of a fleabite to the lymph nodes, where the rampage truly begins.

Researchers who’ve been studying the bacteria say the... Read More
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