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Of Planes, Microbes and Clocks

New research shows how disruption of human biological clock can have negative impact on human intestinal micobiome and in turn lead to metabolic dysfunctions such as weight gain and diabetes. Read More

Altered milk protein can deliver AIDS drug to infants

A novel method of altering a protein in milk to bind with an antiretroviral drug promises to greatly improve treatment for infants and young children suffering from HIV/AIDS, according to a researcher in Penn State's College of Agricultural Sciences.

That's critical because an estimated 3.4 m... Read More

MWV Episode 88 - This Week in Virology #300 - So Happy Together

This Week in Virology, the podcast about viruses, celebrated its 300th episode on Tuesday, August 26, 2014 with a live recording at the Washington, DC headquarters of the American Society for Microbiology. This special episode features the TWiV hosts Vincent Racaniello, Dickson Despommier, Al... Read More

Ebola in DRC: a new strain of the virus

While an Ebola epidemic has been raging in West Africa since March 2014, an outbreak of this haemorrhagic fever occurred in the Democratic Republic of the Congo (DRC) in August, leaving fears over the virus' spread to Central Africa. A study by the IRD, the Institut Pasteur, the CNRS, the CIRMF... Read More

Life on a Pig's Skin

How frequently do microbes exchange genes when living on a host? This question has been on my mind lately. Broadly speaking, the discovery of horizontal gene transfer (HGT) revolutionized the way we think about prokaryotic evolution. No more could we think only of inheritance via vertical descen... Read More

"Bioleaching" bugs present viable mining method

Salt and acid-tolerant bacteria with the potential to be used in mining processing have been uncovered in the Wheatbelt.

The bugs were found during a "bio-prospecting" survey near Merredin and are likely to become more important in WA in coming decades as high-grade ore runs out.
CSIRO envir... Read More

TWiP 79: Across the river and into the trees

Vincent and Dickson discuss the spread of P. knowlesi in Malaysia, and how Leishmania parasites protect the sandfly gut from bacterial infection.


Hosts: Vincent Racaniello and&nbs... Read More

Why CRISPR Doesn't Work in E. coli

We received this query:

»I enjoyed the article on your blog 'Six Questions About CRISPRs' by Merry Youle. I am an ex-lambdologist, having quit phage lambda in the early 70s and moved to GM-plants. There is one thing about CRISPR that I do not understand: Why did lambdologists not find CRISPR?... Read More

Worse Than The Bite

City dwellers across the U.S. might agree on one common enemy: bedbugs. But hey, not to worry, right? "Bedbugs are not known to spread diseases, but bites can be very itchy and irritating." Or so says the New York City Department of Health. But that assertion may not be true. Because a new study... Read More

Flu virus key machine: First complete view of structure revealed

Scientists looking to understand – and potentially thwart – the influenza virus now have a much more encompassing view, thanks to the first complete structure of one of the flu virus’ key machines. Knowing the structure allows researchers to finally understand how the machine works as a whole, a... Read More

TWiP 74 letters

 voxsciurorum writes:


Dear water-based life forms:


It is 24 degrees in Overland Park, Kansas and I am looking at a slide labeled "Giardia lamblia", part of a museum exhibit on water and human (over) use of water.


I see a greenish lump. I don't kno... Read More

TWiP 79 letters


Jesse writes:


Doctors TWiP,


I came across this paper and thought it sounded interesting for a discussion on TWiP:


Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection
Read More

Pseudomonas aeruginosa with black extracellular pigment

Pseudomonas aeruginosa isolated from sputum into department of Microbiology - Riuniti Hospital Reggio Calabria .
This strain of Pseudomonas secretes brown/black extracellular pigment: pyomelanin.
Photo from D'Aleo Francesco archive. Read More

A virus that melts sea stars

Sea stars are lovely marine invertebrates with a round central body connected to multiple radiating legs (photo credit). In the past year millions of sea stars in the west coast waters of North America have melted into piles of slime and ossicles. Sea star associated densovirus might be the caus... Read More
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