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TWiM #96: A lean, mean sequencing machine

Hosts: Vincent Racaniello


Special guest: Rob Knight


Vincent meets up with Rob Knight to talk about the technology that has... Read More

TWiV 287: A potentially pandemic podcast

Matt updates the TWiV team on MERS-coronavirus, and joins in a discussion of whether we should further regulate research on potentially pandemic pathogens.


Hosts: Vincent Racaniello Read More

Physarum polycephalum Different view

Physarum polycephalum, slime mold, grown in a large perti plate on moist paper towels using oatmeal as the food source. Culture was grown in the dark at room temperature. The paper towel was moistened every day with tap water. After 3 week’s the culture formed sporangia (fruiting bodies). Image ... Read More

Microbiology Christmas Tree

This is a picture of the Christmas tree in the University of Colorado Hospital Microbiology Department.

The tree is adorned with homemade culture plate ornaments (one for each staff member) and topped with a stuffed Staphylococcus aureus microbe. Read More

Carl Woese Dies at 84; Discovered Life’s ‘Third Domain’

Carl Woese, a biophysicist and evolutionary microbiologist whose discovery 35 years ago of a “third domain” of life in the vast realm of micro-organisms altered scientific understanding of evolution, died on Sunday at his home in Urbana, Ill. He was 84.

His death was announced by the Universi... Read More

TWiM 48 Letters

Sierra writes:


Hello Racaniello et al.,


I am a plant pathologist for a vegetable seed company in Washington state.  I listen to TWIM, TWIP and TWIV podcast while I read extensive disease resistance screens.  I started out study... Read More

TWiM #85: Oscillation in the ocean and a Verona integron

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

Bacterial protein in house dust spurs asthma according to NIH study (NIH press release)

A bacterial protein in common house dust may worsen allergic responses to indoor allergens, according to research conducted by the National Institutes of Health and Duke University. The finding is the first to document the presence of the protein flagellin in house dust, bolstering the link betw... Read More

The sorceress’s apprentice

ANYONE who walks in the woods will be familiar with witches’ brooms (pictured). Many trees sport these bushy tumours, which have a variety of causes. An important one is a group of bacteria called phytoplasma that are, in turn, carried from plant to plant by sap-sucking insects such as leafhoppe... Read More

"E. coli Happens"

E. coli was grown on MacConkey Agar (MAC) at 37 degrees for 24 hour. MAC is a Selective and Differential media used to inhibit G+ growth and some G- bacteria as well as identify and isolate lactose fermenting G- enteric bacteria mainly Enterobacteriaceae. Strong lactose fermentation produces pi... Read More

Thank Your Gut Bacteria For Making Chocolate 'Healthy'

Boy, it's a good time to be a dark chocolate lover.

We've noted before the growing evidence that a daily dose of the bitter bean may help reduce blood pressure. There also seems to be a link between a regular chocolate habit and lower body weight.

Now scientists are offering an explanation... Read More

Vibrio cholerae serotype O1 ogawa isolated on TCBS agar in Sukraraj Tropical and Infectious Hospital , Kathmandu , Nepal .

Vibrio cholerae was isolated in the capital city Kathmandu , where as it causes cholerae endemic in certain remote parts in the country every year . Vibrio cholerae O1 ogawa serotype was isolated and identified after growth in TCBS agar and subcultured on HIA plate and performed oxidase test (+... Read More

Get to know the bacteria and viruses that call your body home

Are you willing to take a close look at yourself for science?

A really, really close look?

A team of scientists in the Bay Area is inviting citizen scientists to join them in a quest to create the largest database of human microbiomes in the world.

The human microbiome is the ecosystem ... Read More

New SARS-like virus discovered before it causes outbreak (from October)

Four months ago, a mucus sample arrived in Dr. Ali Mohamed Zaki’s laboratory in Saudi Arabia.

The mucus had been coughed up by a 60-year-old Saudi Arabian man with a strange case of pneumonia. He had been admitted to the Dr. Soliman Fakeeh hospital in Jeddah on June 13; soon after, his kidney... Read More

Baby's first microbiology book!

Microbiologist parents of newborns or expecting microbiologists now have a way to indoctrinate their wee little ones with an exciting new book for infants entitled "Baby's First Microbiology Book." Help baby learn about all the important little creatures! The pictures are: a microscope, bacteria... Read More

BacterioFiles 158 - Partners Provide Protein

This episode: Different bacteria working together can thrive better than when working alone!


(9.9 MB, 10.75 minutes)


Show notes: 
News item/ Read More

Mycobacterium smegmatis Acid Fast Stain

Acid Fast stain done on a mix of Staphylococcus aureus and Mycobacterium smegmatis. Carbol fuchsin was applied to the smear and set over a steaming water bath for 10 min to help penetrate the mycolic acid in the cell wall, then rinsed with acid alcohol which washes the carbol fuchsin out of al... Read More

TWiV 215: Illuminating rabies and unwrapping a SARI

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Hosts: Vincent Racaniello, Alan Dove, and Read More

Measles Vaccine Given With a Microneedle Patch Could Boost Immunization Programs

Measles vaccine given with painless and easy-to-administer microneedle patches can immunize against measles at least as well as vaccine given with conventional hypodermic needles, according to research done by the Georgia Institute of Technology and the Centers for Disease Control and Prevention... Read More

How Bacteria Talk to Each Other and Our Cells

Bacteria talk to each other using N-acylhomoserine lactones (AHLs) as quorum sensing (QS) signals. This signaling allows the bacteria to control gene expression of virulence factors and biofilms once a critical density has been achieved. This phenomenon, quorum sensing, is important when an infe... Read More
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