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Drug Combo Cuts Malaria Risk in HIV Patients

Treatment with lopinavir/ritonavir (Kaletra) reduced the risk that HIV-infected children would become co-infected with malaria, researchers said here.

Compared with treatment based on non-nucleoside reverse transcriptase inhibitors (NNRTIs), therapy with the protease inhibitor-based combinati... Read More

Researcher seeks to understand link between obesity, flu severity

The recent H1N1 flu pandemic was found to be particularly dangerous to obese people, and a Wayne State University researcher is looking for clues as to why.

Emily Martin, Ph.D., assistant professor of pharmacy practice in the Eugene Applebaum College of Pharmacy and Health Sciences, has begun... Read More

Arsenic-loving bacteria? New studies contradict report of bugs that seemed to break the rules

It was a provocative finding: strange bacteria in a California lake that thrived on something completely unexpected — arsenic. What it suggested is that life, a very different kind of life, could possibly exist on some other planet.

The research, published by a leading scientific journal in 2... Read More

Cellular Aging

A protein called tubulin (green) accumulates in the center of a nucleus (outlined in pink) from an aging cell. Normally, this protein is kept out of the nucleus with the help of gatekeepers known as nuclear pore complexes. But NIGMS-funded researchers found that wear and tear to long-lived compo... Read More

Reform falters after Europe’s E. coli scare

One year on from Europe’s worst recorded outbreak of Escherichia coli infection, governments have made little progress towards improving the monitoring and reporting systems that allowed the crisis to drag on for weeks. The disease, which was spread by contaminated fenugreek sprouts, swept acros... Read More

Single mumps vaccine making a comeback to the UK - but is it better or worse than what we have?

Due to low uptake of the MMR vaccine across the world, we have seen a dramatic rise in the number of cases of measles and mumps. These have gone against efforts to eradicate these diseases. Perceived safety concerns have led to the rise in uptake of single vaccines and thus for a number of years... Read More

Oddly Microbial: 86 Million Year-Old Deep Seabed Mystery Cells

Life in a high-pressured environment with practically nothing to eat might be ok for high-fashion models, but it’s an unlikely lifestyle choice for a single cell whose usual overriding goal is to become two cells. Yet the largest living ecosystem on Earth—the deep biosphere—is comprised of micro... Read More

Cells on the move

Cells on the move reach forward with lamellipodia and filopodia, cytoplasmic sheets and rods supported by branched networks or tight bundles of actin filaments. Cells without functional lamellipodia are still highly motile but lose their ability to stay on track, report researchers at the Stower... Read More

New approach of resistant tuberculosis

Scientists of the Antwerp Institute of Tropical Medicine have breathed new life into a forgotten technique and so succeeded in detecting resistant tuberculosis in circumstances where so far this was hardly feasible. Tuberculosis bacilli that have become resistant against our major antibiotics ar... Read More

How Bacteria Sense Salt Stress

Scientists' finding is a major breakthrough in understanding a decades-old problem of how bacteria detect environmental changes.

A team of scientists led by Assistant Professor Ganesh S Anand and Professor Linda J. Kenney from the National University of Singapore (NUS) Department of Biologica... Read More

Slo-mo microbes extend the frontiers of life

Community in the deep seabed uses so little oxygen that it is no longer clear where the lower bound for life lies.

Most humans would struggle to last for much more than a minute under water without coming up for air, whereas some seals can manage more than an hour — but a microbial community ... Read More

A novel imaging technique sheds new light on bacterial mobility and adhesion

A scientific endeavour carried out by two French groups belonging to INSERM and CNRS at Aix-Marseilles University shows for the very first time that both bacterium adhesion to and bacterium motion on a surface are driven by the same mechanism (see paper in PNAS: "Wet-surface–enhanced ellipsometr... Read More

When dying, bacteria share some characteristics with higher organisms

Do bacteria, like higher organisms, have a built-in program that tells them when to die? The process of apoptosis, or cell death, is an important part of normal animal development. In a new study published March 6 in the online, open-access journal PLoS Biology, Hanna Engelberg-Kulka and colleag... Read More

Deadly Bat Fungus in Missouri, Farthest West Yet

A disease that has killed millions of bats across multiple states and Canada has been found in Missouri, marking its advent west of the Mississippi River and spelling possible trouble for agriculture in the region, officials said Monday.

White nose syndrome has been confirmed in three bats in... Read More

J&J seeks OK for first drug against resistant TB

Johnson & Johnson said Monday that it is seeking U.S. approval for the first new type of medicine to fight deadly tuberculosis in more than four decades.

The experimental drug, called bedaquiline, also would be the first medicine specifically for treating multi-drug-resistant tuberculosis. Th... Read More

Protein proves to be vital in immune response to bacteria

A team of researchers led by scientists at Rockefeller University have discovered that a protein once thought to be mainly involved in antiviral immunity is in fact more important in fighting bacterial infections and could provide new mechanisms for treating diseases like tuberculosis, which is ... Read More

Natural Intestinal Flora Strengthens Immune System

Signals from natural intestinal bacteria are necessary for an effective immune response to various viral or bacterial germs. This was the result of experiments by a research team led by Prof. Dr. Andreas Diefenbach and Stephanie Ganal at the Institute of Medical Microbiology and Hygiene of the F... Read More

Scientists reveal how natural systems limit the spread of "cheating" bacteria

In the first field study of its kind researchers at Royal Holloway, University of London and the University of Oxford have investigated the competitive dynamics of pathogenic and non-pathogenic strains of bacteria.

Bacteria are increasingly seen as living and interacting in groups and sharing... Read More

Fourth of July: American Presidents and Infectious Diseases

Happy Fourth of July! In honor of this historic holiday we’ve compiled a list showing how infectious diseases and vaccines have affected the lives of our most heralded leaders – the American presidents. These concise accounts are evidence that diseases can strike anyone, anywhere at any time, an... Read More

Parasite of the Day: Xenopsylla ramesis

There is no parasite that is universally infective, even generalist parasites that can infect many different host species are usually limited to a particular taxonomic group - such as fish, insects, or mammals. Some parasites may infect a broad spectrum of hosts during one stage of their life-cy... Read More

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