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Building the perfect bug

This past February I was interviewed by the Australian Broadcasting Company on the topic of the Fouchier and Kawaoka experiments on avian influenza virus H5N1. The video, Building the Perfect Bug, has been released by Journeyman Pictures and includes interviews with S.T. Lai, Laurie Garrett, Mic... Read More

Friendly Fungi: Elucidating the fungal biosynthesis of stipitatic acid

In a tale worthy of Sherlock Holmes, scientists in the School of Chemistry at the University of Bristol, UK have solved a biochemical mystery that had previously proven elusive for 70 years: How the fungus Talaromyces stipitatus produces stipitatic acid (6), which is a tropolone, one of an atypi... Read More

100 trillion good bacteria call human body home

In the search for new life, scientists have studied the depths of the ocean and the lips of steaming volcanoes. They've looked on Mars and the moons of Jupiter, and even planets beyond this solar system.

Dr. David Relman went searching inside his own mouth. On a routine dental visit in 1998, ... Read More

HIV and TB at the White House (photo)

Photo taken by Joshua Yospyn for WJLA TV at the We Can End AIDS march in Washington, D.C. Read More

The Rise of Genomic Superspreaders

One hundred million years ago the earth’s climate was much warmer than today and vast inland seas stretched across entire continents. The land was dominated by charismatic megafauna that would one day serve as inspiration for Sir Arthur Conan Doyle’s novel The Lost World. This period is commonly... Read More

Norton Zinder, 1928-2012

Norton Zinder made two important discoveries in the field of virology. While a Ph.D. student with Joshua Lederberg at the University of Wisconsin-Madison he found that viruses of bacteria (bacteriophages) could move genes from one host to another, a process called transduction. Later in his own ... Read More

Replication of immunodeficiency virus in humans

The acquired immunodeficiency syndrome (AIDS) pandemic is caused by the human immunodeficiency virus (HIV-1), which attacks the immune system and leaves infected individuals susceptible to opportunistic infections. AIDS and HIV-1 are thought to have a relatively short history in humans, with the... Read More

London prepares for Olympian disease-monitoring task

As the world’s athletes limber up for the forthcoming Olympic games in London, infectious-disease experts are preparing for their own trials. Their competition is with the diseases that millions of athletes, officials, media and spectators bring with them as they converge from across the globe o... Read More

Yankee ‘invaders’ threaten UK’s crayfish

Better resistance to parasites and a less fussy diet are allowing aggressive signal crayfish from the US to threaten white-clawed crayfish native to Yorkshire.

The Yorkshire crayfish suffers from two parasites: plague, which is carried by the American invader, and porcelain disease that makes... Read More

What Happened to Our Friendly Enterococci?

Enterococci had been generally regarded as benign commensals, a part of our healthy intestinal microbiota. They were even invited in, being used as probiotics. But then, in the late 1970s, the first multiple drug-resistant strains appeared, and vancomycin-resistant strains followed in 1981. In r... Read More

How hosts recognize bacteria

We are surrounded by bacteria, viruses, fungi and parasites. The fact that we nevertheless do not fall prey to infections is thanks to certain cellular sensor molecules such as toll-like receptors (TLR), which recognize the molecular structure of pathogens and intercede by ensuring an often comp... Read More

Bacterial Vaginosis Is Associated with Higher Risk of Female-to-Male Transmission of HIV

An investigation led by UCSF has found that the risk of female-to-male HIV transmission is increased three fold for women with bacterial vaginosis, a common disorder in which the normal balance of bacteria in the vagina is disrupted.

The new research assessed the association between bacterial... Read More

Influenza H5N1 virus versus ferrets, round two

The second of two papers on avian influenza H5N1 virus that caused such a furor in the past year was published today in the journal Science. I have carefully read the paper by Fouchier and colleagues, and I assure you that it does not enable the production of a deadly biological weapon. The resu... Read More

Study Shows First N.C. Case of Feral Pig Exposure to Nasty Bacteria

A North Carolina State University study shows that, for the first time since testing began several years ago, feral pigs in North Carolina have tested positive for Brucella suis, an important and harmful bacteria that can be transmitted to people.

The bacteria are transmitted to humans by uns... Read More

Bacteria outbreak in Northern Europe due to ocean warming, study says

Manmade climate change is the main driver behind the unexpected emergence of a group of bacteria in northern Europe which can cause gastroenteritis, new research by a group of international experts shows.

The paper, published in the journal Nature Climate Change on Sunday, provided some of th... Read More

Mind-controlling virus forces parasitic wasp to put all its eggs in one basket

In a French meadow, a creature that specialises in corrupting the bodies of other animals is getting a taste of its own medicine.
Leptopilina boulardi is a wasp that lays its eggs in fly maggots. When the wasp grub hatches, it devours its host form the inside out, eventually bursting out of its... Read More

Milestones in the Effort to Eradicate Polio [Timeline]

Advances in the 1950s and 1960s, including unprecedented cooperation between Soviet and U.S. scientists, allowed polio to be eradicated throughout the Americas by 1994 and all of Europe in 1998. Eliminating the crippling scourge has been more difficult, however, in some parts of Africa and Asia.... Read More

Princeton University researchers develop tooth attachment that detects bacteria

It may not be the latest style in bovine bling, but researchers at Princeton University say a golden tattoo attached to a cow’s tooth could one day tell you something about your health.

The remote sensing device has the ability to detect a single bacterium, and to demonstrate, scientists at P... Read More

Vorticella

A single Vorticella species. Taken from the Wistreich Collection, appearing exclusively on MicrobeWorld. Read More

HPV Vaccine Reduces Infection, Even in Unvaccinated: Evidence of 'Herd' Protection

The HPV vaccine not only has resulted in a decrease in human papillomavirus infection in immunized teens but also in teens who were not immunized.

The study is believed to be the first to show a substantial decrease in HPV infection in a community setting as well as herd protection -- a decre... Read More

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