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MWV Episode 94 - TWiM #99: Careers in Biodefense
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New drugs for bad bugs

Washington University in St Louis chemist Timothy Wencewicz says we’ll stay ahead of antibiotic resistance only if we find drugs with new scaffolds, or core chemical structures. One promising candidate, an antibiotic made by a bacterium than infects plants, caught his attention because it contai... Read More

Serratia marcescens/Escherichia coli mix

Serratia marcescens/Escherichia coli mix grown on TSA for 48 hrs. Serratia marcescens grows red due to prodigiosin and Escherichia coli grows opaque white. Read More

Battling Infection With Microbes

The human relationship with microbial life is complicated. At almost any supermarket, you can pick up both antibacterial soap and probiotic yogurt during the same shopping trip. Although there are types of bacteria that can make us sick, Caltech professor of biology and biological engineering Sa... Read More

Virtual bees help to unravel microbial and other causes of colony decline

What effect does the varroa mite, and the viruses it transmits, have on bee colonies? To find out, scientists have developed a new computer model to that simulates a honey bee colony over the course of several years.
Shown in the video on this page, the BEEHAVE model was c0-funded by BBSRC and... Read More

Arctic bacteria gene swap to detoxify mercury

On the list of substances you really don’t want to mess with, elemental mercury is pretty high up. Inhalation or absorption of the volatile metal can quickly lead to irreversible poisoning. Unfortunately, Hg is also a hallmark of industrial society.....Mercury-resistant bacteria carry a collecti... Read More

The Ebola Outbreak: 'A Dress Rehearsal For The Next Big One'

Until this year, the world had recorded 1,640 deaths from Ebola since the virus was discovered in 1976.

Then Ebola appeared in West Africa.

So far this year, 887 people have died of Ebola in West Africa, the World Health Organization said Monday.

To put that into perspective, more than ... Read More

TWiV 299: Rocky Mountain virology

Vincent visits the Rocky Mountain Laboratories in Hamilton, Montana and speaks with Marshall, Sonja, and Byron about their work on tick-born flaviviruses, innate immunity, and prion diseases.


Host: Vincent ... Read More

TWiP 77 letters

Andy writes:


Dear Professors,


I have been following TWIP for several years. I am a software engineer and parasitology is only an avocation. As an undergraduate in the early 80's I discovered my love of history of science and ecology, although I continued the p... Read More

Protein's "hands" enable bacteria to establish infection, research finds

When it comes to infecting humans and animals, bacteria need a helping hand.

Kansas State University biochemists have found the helping hand: groups of tiny protein loops on the surface of cells. These loops are similar to the fingers of a hand, and by observing seven individual loops on the ... Read More

TWiV 314: Einstein goes viral

Vincent travels to Albert Einstein College of Medicine where he speaks with Kartik, Ganjam, and Margaret about their work on Ebolavirus entry, a tumor suppressor that binds the HIV-1 integrase, and the entry of togaviruses and flaviviruses into cells.


Host:  Read More

When Will We Have a Vaccine for Ebola Virus?

The latest outbreak of Ebola virus in west Africa is the worst ever—as of Monday, it had infected more than 1,200 people and claimed at least 672 victims since this spring. Guinea, Liberia and Sierra Leone all have confirmed cases. An official at Doctors Without Borders has declared the outbreak... Read More

Stanford bioengineer develops a 50-cent paper microscope

The Foldscope is a fully functional microscope that can be laser- or die-cut out of paper for around 50 cents.

This bookmark-sized microscope can be assembled in minutes, includes no mechanical moving parts, packs in a flat configuration, is extremely rugged and can be incinerated after to s... Read More

Fluid Thioglycollate Media

Organisms grown in Fluid Thioglycollate Media w/out resazurin dye is a reducing media that uses sodium thioglycollate to chemically combine with dissolved oxygen to deplete the oxygen in the media. All organism except for Neisseria sicca were grown for 48 hours at 37 degrees C. Neisseria sicca i... Read More

Avoid Getting Sick: Top 8 Germiest Public Places Exposed

Worried about you or your kids picking up the flu virus or other common illnesses at school, in restrooms or at the mall? There’s good reason: Viruses and bacteria run rampant on the surfaces you touch every day. We blow the lid on the 8 germiest public places and give you expert tips to avoid g... Read More

New research shows that bacteria survive longer in contact lens cleaning solution than previously thought

Each year in the UK, bacterial infections cause around 6,000 cases of a severe eye condition known as microbial keratitis - an inflammation and ulceration of the cornea that can lead to loss of vision. The use of contact lenses has been identified as a particular risk factor for microbial kerati... Read More

New Springtime Flu Strain Going Around New York

Thought you only had to deal with allergies these days? Well, maybe you've noticed some friends or work colleagues calling in sick lately—that may be because there's another flu strain making the rounds.

According to the Centers for Disease Control, influenza B is accounting for 55% of all vi... Read More

Live/Dead Stain Microscopy

Tannery tanning fluid sample stained with Live/Dead BacLight under UV light. Either 40x or 100x oil immersion. Green bacteria indicate living cells, while Orange bacteria indicate dead cells. Some of the green cells were moving around even after staining! Read More

Microbe/Mineral Affinities

This is a paper from the Geomicrobiology lab at the Jackson School of Geosciences at the University of Texas at Austin. It was recently published in a special issue of Geomicrobiology Journal focused on geomicrobiology of subsurface microorganisms in cave environments.

In this study we attemp... Read More

Ebola Virus: A Grim, African Reality

There’s nothing like an outbreak of Ebola virus disease to bring a small, struggling African nation to international notice. One week we couldn’t place it on a map; the next week, after Ebola virus disease strikes, we know the body count and the name of the capital and whether its airport has cl... Read More

Why are bacteria all the same size

Just when we think we know everything, a story comes along to remind us that there is something fundamental--and seemingly elementary--that we still haven't figured out. “Why are we the size we are? Why are our organs the size they are? Why are the cells in those organs a stereotypical size? Wha... Read More
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