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TWiM 125 Letters

Inspired by William:


Dear TWiMers;
Greetings from Berkeley where miracle March (water-wise) was perhaps half a miracle, but that is definitely better than none. At least we will not run out of water this summer.


I found this quasi-synthetic biology result... Read More

TWiV 387: Quaxxed

Hosts: Vincent RacanielloDickson DespommierAlan Dove, and  Read More

BacterioFiles 256 - Virus Versus Virus

This episode: Viruses can cause host cells to inhibit other viruses!


(8 MB, 8.75 minutes)


Show notes: 
Journal Paper:

Chiba S, Suzuki N. 2015. Highly act... Read More

How long have primates been infected with viruses related to HIV?

Disease-causing viruses engage their hosts in ongoing arms races: positive selection for antiviral genes increases host fitness and survival, and viruses in turn select for mutations that counteract the antiviral host factors. Studying such adaptive mutations can provide insights into the distan... Read More

First hospital-based rapid detection Zika test now available

Collaboration between two Texas Medical Center institutions has resulted in today's release of the country's first hospital-based rapid tests for the Zika virus. Read More

Rapid Ebola Test Could Play Key Role in Efforts to End Lingering Outbreak

Research presented at the 2015 AACC Annual Meeting & Clinical Lab Expo will expand on the studies that led to a fingerprick Ebola test becoming the first and only rapid diagnostic for this disease to receive approval from the World Health Organization (WHO). This test could prove vital to breaki... Read More

8th grader petri dishes - seeking help to identify colonies

I did a study of hand washing and hand sanitizer. Is anyone on the list willing to help me identify what grew from my unwashed and even washed hands? I attach three photos representing the yellow, white and orange growths found after several days on agar plates. Thank you so much in advance. Read More

New Diversity for Lager Beers

Washington, DC – September 25, 2015 - Unlike ales, lager beers differ little in flavor. But now, by creating new crosses among the relevant yeasts, Kevin Verstrepen, PhD, Stijn Mertens, and their collaborators have opened up new horizons of taste. The research is published in the September 25 Ap... Read More

A Green Thumb for Ocean Microbes

MIT-WHOI Graduate student Kristen Hunter-Cevera describes the challenges and obstacles involved with growing marine microbes (in her case, Synechococcus) in a laboratory setting, and outlines the value of her research in understanding marine biogeochemistry. Read More

Community ecology can advance the fight against infectious diseases

Despite continued medical advances, infectious diseases kill over 10 million people worldwide each year. The ecological complexity of many emerging disease threats--interactions among multiple hosts, multiple vectors and even multiple parasites--often complicates efforts aimed at controlling dis... Read More

Zolav®: A new antibiotic for the treatment of acne

A scientific paper released today in the Journal of Drug Design, Development and Therapy show the effectiveness of Zolav®, a new antibiotic, in treating acne. Read More

Chestnut leaves yield extract that disarms deadly staph bacteria

Leaves of the European chestnut tree contain ingredients with the power to disarm dangerous staph bacteria without boosting its drug resistance, scientists have found. Read More

TWiM 127 Letters

Stefan writes:


Just discovered this nice episode.
Well made and nicely discussed comment on our pack-hunting paper; quick reply to the question what would happen if you add one single amoebae: it would multiply and a clonal pack would do the same thing as observe... Read More

Interrupting the transmission cycle: A protein required for dengue virus infection of mosquitoes

There is currently no approved specific treatment or vaccine for dengue fever, and an estimated 2 billion people are at risk for being bitten by Aedes mosquitoes and infected with the dengue virus (DENV). A study published on October 22nd in PLOS Pathogens introduces a candidate target for a tra... Read More

Cells in Senescence State May Help Slow down Aging and Cancer Treatment

BOC Sciences-Senescence means a state where cells stop further development in their function but clean themselves and remove the extra substance. Scientists found that when cells go into this stage, the growth rate of tumor would slow down, which is true of aging. The finding was made on the lev... Read More

Ebola crisis provides framework for responding to outbreaks like Zika virus

PRINCETON, N.J.--As world leaders grapple with containing the Zika virus, the Ebola epidemic in West Africa provides valuable lessons for how to respond to infectious disease epidemics, according to a policy report published by researchers at Princeton University and the Wellcome Trust. Read More

Link between small mammals and evolution of hepatitis A virus to humans discovered

Researchers at the University of North Carolina at Chapel Hill (UNC-Chapel Hill) are part of an international team led by the University of Bonn, Germany, who have found a link between the origin of hepatitis A virus (HAV) and small mammals. With the emergence of Ebola virus from bats and hantav... Read More

Following Maternal Transmission, Group B Strep Mutates to Sicken Infants

Washington, DC - August 18, 2015 - Group B streptococcus, a mostly benign inhabitant of healthy adults, is one of the world’s leading causes of neonatal sepsis and meningitis. A team of French investigators has now shown that such cases might occur when the microbe mutates within the infant foll... Read More

TWiM #130: Interkingdom interactions at ASM Microbe

The TWiMers get together at ASM Microbe 2016 in Boston to speak with David and Vanessa to talk about their work on regulation of bacterial virulence in the gut by bacterial adrenergic sensors, and the physiological mechanisms that make us ill and that help us recover.


Hosts: Read More

Viral variation in single cells

It is well known that virus populations display phenomenal diversity. Virus populations are dynamic distributions of nonidentical but related members called a quasispecies. This diversity is restricted in single cells, but is restored within two infectious cycles. Read More
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