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Proof of life: Reevaluating oldest known Archean trace fossil for indications of early biology

In the hunt for early life, geobiologists seek evidence of ancient microbes in the form of trace fossils – geological records of biological activity – embedded in lavas beneath the ocean floor. Filamentous titanite (a calcium titanium silicate mineral) microtextures found in 3.45 billion-year-ol... Read More

TWiM 87 Letters

Varun writes:


Greetings TWiM Profz,


As a perso... Read More

BacterioFiles 205 - Colon Community Counterattacks Cholera

This episode: Microbes in the human gut seem to prevent/inhibit cholera!


(10.5 MB, 11.5 minutes)


Show notes: 
Journal Paper

... Read More

Lipid Agar

Lipid Plate/Tributyrin Agar used to test for an organisms ability to produce the exoenzyme lipase which breaks down the lipids in the agar creating a clear zone around the organism. (A) Serratia marcesens, lipid hydrolysis, indicated by a zone of clearing around the growing colony, as well as th... Read More

How U.S. Hospitals Are Planning To Stop The Deadly MERS Virus

In the past month, Middle East Respiratory syndrome has morphed from a little-known disease in the Arabian Peninsula to a major global health concern, with more than 300 cases in Saudi Arabia in April, 54 of them fatal.

Two cases have been reported in the U.S. as well — one in Indiana and one... Read More

2,300 tubes containing SARS virus samples missing in France

A major French biomedical research body, the Pasteur Institute, have launched an investigation into the disappearance of some 2,300 test tubes containing samples of the SARS virus. The loss was discovered during an inventory.

The Pasteur Institute filed a so-called 'complaint against X' on Mo... Read More

The protective milk shot – How mother’s milk protects piglets from parasite infections

Coccidiosis is a serious disease in new-born piglets. Caused by the parasite Cystoisospora suis, it exclusively infects pigs and often causes severe diarrhoea in suckling piglets. Parasitologists at the Vetmeduni Vienna have developed a new strategy for protecting the piglets: They infected sows... Read More

Slime producing Staphylococcus epidermidis on Congo Red agar

Slime production by Staphylococcus epidermidis on Congo Red agar; demonstrated by black colored colonies. Slime production is one of the most important virulence factors produced by Coagulase negative Staphylococci.

The colonies of slime non-producing strains remain pink to red.
Read More

Bacterial Nanowires: Not What We Thought They Were

New videos of morphing bacteria reveal that the strange, distinguishing features of so-called “electric bacteria” aren’t quite what they at first appeared to be.

For the past 10 years, scientists have been fascinated by a type of “electric bacteria” that shoots out long tendrils like electric... Read More

Researchers create better methods to detect E. coli

Kansas State University diagnosticians are helping the cattle industry save millions of dollars each year by developing earlier and accurate detection of E. coli.

Lance Noll, master's student in veterinary biomedical science, Greensburg; T.G. Nagaraja, university distinguished professor of di... Read More

BacterioFiles 193 - Milk Modifies Monkey Microbes

This episode: Being raised with their mother and breastmilk vs. bottle-fed in a nursery significantly affects macaque microbiomes and their immune system profile!


(7.7 MB, 8.4 minutes)


Show notes: 
Read More

TWiV 299: Rocky Mountain virology

Vincent visits the Rocky Mountain Laboratories in Hamilton, Montana and speaks with Marshall, Sonja, and Byron about their work on tick-born flaviviruses, innate immunity, and prion diseases.


Host: Vincent ... Read More

My experience with Foldscope, the paper microscope.

My experience with Foldscope, the paper microscope. See the images of insects, parasites, vegetal and animal tissues and cells, yeast, bacteria and (almost) virus (the cytopathic effect), with Foldscope, the paper microscope (text in Spanish). Read More

A WORD on the constraints of influenza virus evolution

Evolution proceeds by selection of mutants that arise by error-prone duplication of nucleic acid genomes. It is believed that mutations that are selected in a gene are dependent on those that have preceded them, an effect known as epistasis. Analysis of a sequence of changes in the influenza vir... Read More

TWiV 312: She sells B cells

The TWiVbolans discuss the finding that human noroviruses, major causes of gastroenteritis, can for the first time be propagated in B cell cultures, with the help of enteric bacteria.


Hosts:  Read More

TWiV 303: Borna this way

The TWiV team discusses transmission of Ebola virus, and inhibition of Borna disease virus replication by viral DNA in the ground squirrel genome.


Hosts: Vincent Racaniello Read More

Why are bacteria all the same size

Just when we think we know everything, a story comes along to remind us that there is something fundamental--and seemingly elementary--that we still haven't figured out. “Why are we the size we are? Why are our organs the size they are? Why are the cells in those organs a stereotypical size? Wha... Read More

TWiP 79 letters


Jesse writes:


Doctors TWiP,


I came across this paper and thought it sounded interesting for a discussion on TWiP:


Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection
Read More

Ebola Virus: A Grim, African Reality

There’s nothing like an outbreak of Ebola virus disease to bring a small, struggling African nation to international notice. One week we couldn’t place it on a map; the next week, after Ebola virus disease strikes, we know the body count and the name of the capital and whether its airport has cl... Read More

When Will We Have a Vaccine for Ebola Virus?

The latest outbreak of Ebola virus in west Africa is the worst ever—as of Monday, it had infected more than 1,200 people and claimed at least 672 victims since this spring. Guinea, Liberia and Sierra Leone all have confirmed cases. An official at Doctors Without Borders has declared the outbreak... Read More
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