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TWiV 418: Of mice and MERS

The TWiVsters describe a new animal model for MERS coronavirus-induced acute respiratory distress syndrome, produced by CRISPR/Cas9 editing of the mouse gene encoding an ortholog of the virus receptor.


Hosts:  Read More

A Microbial Death Star

Star Wars – an epic story of war between the forces of good and evil in a galaxy far, far away. The Death Star – the ultimate weapon of destruction. The story is science fiction, but it could be considered an analogy for the constant battle between our immune system and microbial pathogens. Beli... Read More

A Microbial Ocean Feast: Who Ate What?

Single-celled organisms called bacterioplankton spend their lives drifting in open ocean, visible to the naked eye only en masse. But don't be fooled by their slight size: These minuscule critters play a hefty role in the carbon cycle. Heterotrophic microbes, by some estimates, process half of t... Read More

And they're off! An overview of ASM resources on Olympic-related infectious disease reports

The opening ceremony for the Summer Olympics 2016 will be held this Friday, marking the onset of two weeks of competition between the world’s best athletes. The world has been focused on Brazil and its preparedness – not only for the infrastructure required for the games, but also for any potent... Read More

Two birds with one stone: E. faecium cotransfers drug resistance determinants by homologous recombination

The Gram-positive bacterium Enterococcus faecium is a member of the ESKAPE pathogens for which drug resistance has been a growing problem. How E. faecium becomes drug resistant has been a long-standing question, and is the focus of a new study now available in Antimicrobial Agents and Chemothera... Read More

April Showers Bring May Flowers - But Microbes Keep them Growing

Just as humans have a complex relationship with microorganisms, some make us sick while others aid our health, plants too coexist with a mixture of mostly helpful but sometimes harmful microbes.

While geosmin may overwhelm our noses, plants are able to detect a number of compounds produced b... Read More

UNC scientists named to European Union-funded global Zika research consortium

Aravinda de Silva, PhD, professor of microbiology and immunology, and Stefan Metz, PhD, a post-doc in de Silva's lab, make up one of only two U.S. teams to be named to the European Union-funded worldwide initiative. Sponsored by the European Union's Horizon 2020 Programme, the consortium is inve... Read More

Demystifying secondary bacterial pneumonia

In some individuals, an influenza A virus infection can cause asymptomatic Staphylococcus aureus (S. aureus) to travel to the lungs where it can trigger severe, sometimes deadly, secondary pneumonia. S. aureus is one of the most common causes of secondary bacterial pneumonia in cases of seasonal... Read More

Boston subway system covered in microbes, but they're not harmful

As part of its Microbiology of the Built Environment initiative, the Alfred P. Sloan Foundation started funding projects a few years ago that touched on the interaction of microbiology with architecture, buildings or, in the case of Curtis Huttenhower, PhD, an associate professor of computationa... Read More

BacterioFiles 278 - Fungal Family Friends and Foes

This episode: Some fungi change from making plants sick to being helpful to plants! How do plants react to them?


(8.1 MB, 8.8 minutes)


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Microbial responses to land management practices

Microbial communities are essential drivers of soil functional processes such as nitrification and heterotrophic respiration. Although there is initial evidence revealing the importance of soil type in shaping microbial communities, there has been no in-depth, comprehensive survey to robustly es... Read More

How Vibrio cholerae is attracted by bile revealed

A group of researchers from Osaka University, Hosei University, and Nagoya University have revealed the molecular mechanism that Vibrio cholerae, the etiological agent of cholera, is attracted by bile. This group has also successfully detected the ligand binding to the bacteria chemoreceptor in ... Read More

Maternal high-fat diet during pregnancy can affect baby's gut microbes

A new study by researchers at Baylor College of Medicine found that, "babies born to mothers who consumed a high-fat diet during pregnancy had a gut microbiome that was distinctly different from the one in babies of mothers on a non-high-fat diet".
Noteably, researchers found that, "the micro... Read More

Diversity and Activity of Communities Inhabiting Plastic Debris in the North Pacific Gyre

Marine plastic debris is a growing concern that has captured the general public’s attention. While the negative impacts of plastic debris on oceanic macrobiota, including mammals and birds, are well documented, little is known about its influence on smaller marine residents, including microbes t... Read More

Additives to boost vaccine responses not sufficient to protect obese mice from influenza

At St. Jude Children’s Research Hospital in Memphis, Tenn., scientist Stacey Schultz-Cherry has been studying the impact of obesity on influenza severity.

“We saw during the 2009 flu pandemic that there’s an epidemiological link between people getting severe flu and being obese,” says Schultz... Read More

ASM holds Zika press conference

Tomorrow begins a Special President’s Edition ASM Conference, hosted by the American Society for Microbiology in collaboration with the American Society for Virology. The conference, “What Does the Biology of Flaviviruses Tell Us About Zika: The Importance of Fundamental Virus Biology” highlight... Read More

Fighting Zika with Functional Fashion

Function is often thought of as the tradeoff for high fashion, but who says you can’t have both? Fawn Jordan, 2016-2017 DC Fashion Incubator Designer in Residence, is seeking to unite the two to help protect women against potentially Zika-transmitting mosquitoes. Her recent collection combines t... Read More

What does the structure reveal about a colony collapse disorder-associated virus

Colony collapse disorder (CCD) has caused such a profound drop in honeybee populations that even the U.S. Congress is addressing the issue: Senator Jeff Merkley (D-Oregon) has proposed the Pollinator Recovery Act to preserve pollinator habitat. The rapid decline in these important pollinators af... Read More

Bacteria in your mouth may trigger arthritis

Investigators at Johns Hopkins report they have new evidence that a bacterium known to cause chronic inflammatory gum infections also triggers the inflammatory “autoimmune” response characteristic of chronic, joint-destroying rheumatoid arthritis (RA). The new findings have important implication... Read More

TWiV 411: Chicken runs

The TWiVeroos examine a reverse spillover of Newcastle disease virus vaccines into wild birds, and identification of a protein cell receptor for murine noroviruses.


Hosts: Vincent Racaniel... Read More

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