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Breast cancer drug beats superbug

Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have found that the breast cancer drug tamoxifen gives white blood cells a boost, better enabling them to respond to, ensnare and kill bacteria in laboratory experiment... Read More

A biofilm model that accounts for cell aggregates

Whether you’ve Google-searched “biofilm” to learn more yourself, taken courses covering the subject, or are deeply embedded in biofilm-related research, you’ve probably encountered a model similar to the one below, which represents biofilm maturation. In the current model, a biofilm begins with ... Read More

TWiV 396: Influenza viruses with Peter Palese

Vincent speaks with Peter Palese about his illustrious career in virology, from early work on neuraminidases to universal influenza virus vaccines.


Host: Vincent Racaniello 


Guest:&nbs... Read More

ROVING GENE LETS BACTERIA RESIST ‘LAST’ ANTIBIOTICS

A gene that lets bacteria resist polymyxins—the last line of antibiotic defense we have left—has shown up in widespread bacteria samples from pigs and patients in south China, including strains with epidemic potential. Read More

Asymptomatic people can transmit Dengue viruses to Mosquitos

75% of the ~390 million people infected with dengue viruses present with no symptoms (asymptomatic). It is generally assumed that these asymptomatic infections cannot be transmitted to mosquitos. Not only does this study show that people with asymptomatic infections transmitted the virus to mo... Read More

NIH-sponsored clinical trial of chikungunya vaccine opens

An experimental vaccine to protect against the mosquito-borne illness chikungunya is being tested in a Phase 2 trial sponsored by the National Institutes of Health. Results from an initial trial of the vaccine, which was developed by scientists at the NIH National Institute of Allergy and Infect... Read More

Vitamin D deficiency may limit immune recovery in HIV-positive adults

Athens, Ga. - A University of Georgia researcher has found that low levels of vitamin D may limit the effectiveness of HIV treatment in adults. Read More

Some Flashy Bacteria

Want to impress your lab mates? Flash them with some Kocuria rhizophila and Lactobacillus casei on blood agar. Read More

TWiV 390: Building a better mosquito trap

Project Premonition, a Microsoft Research project that uses drones to capture mosquitoes and analyze them for pathogens, preprint servers, and three mouse models for Zika virus induced birth defects are the topics of this episode hosted by the TWiumvirate and theirs guests Etha... Read More

Study finds that Ebola vaccine is safe and stimulates strong immune response

Baltimore, MD, November 17, 2015--A clinical trial of a new Ebola vaccine (ChAd3-EBO-Z) that resulted from an unprecedented global consortium assembled at the behest of the World Health Organization has found that it is well tolerated and stimulates strong immune responses in adults in Mali, Wes... Read More

Microbiomes could hold keys to improving life as we know it

A consortium of 48 scientists from 50 institutions in the United States - including Pamela Silver, Ph.D., a Core Faculty member at the Wyss Institute for Biologically Inspired Engineering at Harvard University - are calling for a Unified Microbiome Initiative that would span national cross-insti... Read More

Microbial communication over the airwaves

Jean-Paul Latgé originally wanted to know if he could test the breath of patients with Aspergillus infections for volatile compounds produced by the fungus. His group at the Pasteur Institute in Paris thought this might be a new way of diagnosing fungal culprits like Aspergillus fumigatus that o... Read More

New American Academy of Microbiology Report provides recommendations for implementing NGS to clinical microbiology settings

This morning, the American Academy of Microbiology released a report, “Applications of Clinical Microbial Next-Generation Sequencing.” An event was held at the National Press Room to highlight its release. You can read more about the event here, or go here to read recommendations on NGS in a cli... Read More

Using citizen science to engage students

Scientists and science educators now recognize the value in explaining what fields don’t understand, in addition to facts supported by years of experimental data. Citizen science projects, which emphasize accessibility of scientific technologies and methods for everyone, allow people without yea... Read More

Microorganisms Spreading Holiday Cheer

This holiday season, as you open a bottle of your favorite wine to share with family and friends, consider making a toast to Saccharomyces cerevisiae (also known as “brewer’s yeast”) which is a species of yeast that is commonly used for making wine and beer. Yeast is absolutely essential to wine... Read More

BacterioFiles 263 - Germ Jettisoned Jellyfish Genes

This episode: Microscopic parasites of fish and worms actually came from jellyfish-like animals, after losing most of their genome!


(7.7 MB, 8.3 minutes)


Show notes: 
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Preclinical Studies on the Pharmacokinetics, Safety, and Toxicology of Oxfendazole: Toward First in Human Studies

A number of BZ anthelmintics used in veterinary medicine have been considered for transition to human use, including oxibendazole and oxfendazole (OXF). In addition, flubendazole, already approved for use as an intestinal anthelmintic, is also being developed as a treatment against adult filaria... Read More

Identifying milk components that promote a healthy infant microbiome

Breast milk provides an inexpensive, nutrient-filled source of food for babies. Because of this, the American Academy of Pediatrics and the WHO recommend new mothers to exclusively breast feed their babies for the first six months of life, and continue up to two years (supplemented with other fo... Read More

TWiV 398: Permission to be intuitive

Vincent speaks with Sandy Weller about her career and her work on the mechanisms of synthesis, maturation, cleavage and packaging of viral DNA genomes.


Host: Vincent Racaniello 


Guest: ... Read More

Register now for free Mysterious Microbes webinar series starting Jan 14

Want to learn more about the most abundant, diverse, and hidden life on Earth?

Attend the FREE Mysterious Microbes Public Webinar Series and Educator Workshop hosted by CIRES Education Outreach!

These free events feature the cutting-edge research of leading microbial scientist Noah Fierer ... Read More
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