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MWV Episode 94 - TWiM #99: Careers in Biodefense
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This episode: Bacterial antivirus system could treat chronic herpes virus infections!


(10.9 MB, 11.9 minutes)


Show notes: 
Journal Paper


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TWiV 320: Retroviruses and cranberries

Vincent speaks with John Coffin about his career studying retroviruses, including working with Howard Temin, endogenous retroviruses, XMRV, chronic fatigue syndrome and prostate cancer, HIV/AIDS, and his interest in growing cranberries.


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TWiV 307: Ebola aetiology

Tara Smith joins the TWiEBOVsters to discuss the Ebola virus outbreak in west Africa, spread of the disease to and within the US, transmission of the virus, and much more.


Hosts: Vincent Racaniello Read More

Alcaligenes faecalis

Streak plate of Alcaligenes faecalis grown on TSA for 48 hr. Read More

'Paleo Ale' Brewed From Yeast Found On A 40-Million-Year-Old Whale Fossil

A Virginia brewer soon plans to serve a beer made from yeast found hanging out on a 40-million-year-old whale fossil, the blog Symbiartic reports. Depending on your disposition, I imagine you're reacting in one of two ways right now, "Yecchh!" or "Cool!" The beer will be called Bone Dusters Pale... Read More

Interview with Prof. Dr. Dwij Raj Bhatta

Respected Sir,

Microbiology World is a bi-monthly e-magazine, which publish articles based on Microbiology and related fields of Life Sciences. Microbiology World has been established in 2013 and has been supported by several organizations.
I, editor in chief of this magazine, would be glad... Read More

Happy Holidays!

Large TSA plate: yellowish organism is Staph aureus, red organism is Serratia marcescens. Grown for 24 hrs at 37 degrees C. Read More

Energetic immune cells are vital for fighting disease

A good immune system relies on a key ‘energy producing’ protein in immune cells to develop immunity to vaccines and disease, an international team of scientists has found.

The protein, called HuR (human antigen R) is critical for controlling metabolism in B cells, which make antibodies that a... Read More

Bacteria Used to Create Fossil Fuel Alternative

British and Finnish scientists have found a way of generating renewable propane using a bacterium widely found in the human intestine and say the finding is a step to commercial production of a fuel that could one day be an alternative to fossil fuel reserves.

"Although we have only produced ... Read More

TWiM 94 Letters

Kieran writes:


Dear Vincent,


I have just finished listening to TWiM 92 and it was very interesting, as always. It is a pleasure to listen to all of you discuss these fascinating topics.


At the end of this episode, you talk about probiotics because it w... Read More

Antibiotics In Manure Implicated In Human Pathogenic Bacteria In Soil

Researchers have have found that the repeated application of manure contaminated with antibiotics changes the composition of bacteria in the soil.

The focus of the investigation was on sulfadiazine (SDZ), a widely used antibiotic in animal husbandry which enters the soil via manure. The rese... Read More

A system‐level model for the microbial regulatory genome

Microbes can tailor transcriptional responses to diverse environmental challenges despite having streamlined genomes and a limited number of regulators. We present data‐driven models that capture the dynamic interplay of the environment and genome‐encoded regulatory programs of two types of prok... Read More

TWiV 282: Tamiflu and tenure too

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Hosts:  Read More

Swarming Motility of Pseudomonas aeruginosa

Strain: Pseudomonas aeruginosa PA14
Medium: M8 minimal medium agar plates
Incubation Conditions: 48 hours at 37°C
Pseudomonas aeruginosa is a gram-negative, rod-shaped and monoflagellated bacterium that has an incredible nutritional versatility. Swarming motility, a flagellum-dependent behavi... Read More

Antibiotic developed 50 years ago may be the key to fighting ‘superbugs’

Scientists at the University at Buffalo are turning to an old class of antibiotics to fight new superbugs resistant to modern medicine.

A $4.4 million grant from the National Institutes of Health will allow UB researchers to develop new dosing regimens for polymyxin antibiotics.

Developed ... Read More

Algae able to switch quantum coherence on and off

A UNSW-led team of researchers has discovered how algae that survive in very low levels of light are able to switch on and off a weird quantum phenomenon that occurs during photosynthesis.

The function in the algae of this quantum effect, known as coherence, remains a mystery, but it is thoug... Read More

Small microbes almost killed all life on Earth, study suggests

Tiny microbes on the bottom of the ocean floor may have been responsible for the largest extinction event our planet has ever seen, according to a new study.

These microbes of death were so small, that 1 billion of them could fit in a thimble-full of ocean sediment, and yet, they were almost... Read More

TWiV 306: This Week in Ebolavirus

 


The Grand Masters of the TWiV discuss Ebola virus transmission, air travel from West Africa, Ebola virus infectivity on surfaces, the Dallas Ebola virus patient, and Ebola virus in dogs.


Hosts:  Read More

Breakthrough antibacterial approach could resolve serious skin infections

Like a protective tent over a colony of harmful bacteria, biofilms make the treatment of skin infections especially difficult. Microorganisms protected in a biofilm pose a significant health risk due to their antibiotic resistance and recalcitrance to treatment, and biofilm-protected bacteria ac... Read More

TWiV 302: The sky is falling

The TWiVers discuss the growing Ebola virus outbreak in West Africa, and an epidemic of respiratory disease in the US caused by enterovirus D68.


Hosts: Vincent Racaniello Read More

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