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TWiV 401: Vector victorious

Zika virus spreads in the USA, a Zika virus DNA vaccine goes into phase I trials, and how mosquito bites enhance virus replication and disease, from the friendly TWiFolk Vincent, Dickson, Alan, and Kathy.

Hosts:  Read More


A gene that lets bacteria resist polymyxins—the last line of antibiotic defense we have left—has shown up in widespread bacteria samples from pigs and patients in south China, including strains with epidemic potential. Read More

Studies raise questions about impact of statins on flu vaccination in seniors

A new pair of studies suggests that statins, drugs widely used to reduce cholesterol, may have a detrimental effect on the immune response to influenza vaccine and the vaccine's effectiveness at preventing serious illness in older adults. Published in The Journal of Infectious Diseases, the find... Read More

New SARS-like virus can jump directly from bats to humans, no treatment available

Researchers from the University of North Carolina at Chapel Hill have discovered a new bat SARS-like virus that can jump directly from its bat hosts to humans without mutation. However, researchers point out that if the SARS-like virus did jump, it is still unclear whether it could spread from h... Read More

Yet another reason to avoid methamphetamine: negative effects of meth on wound healing

Dr. Luis Martinez was on a dream vacation with his three boys. Far from their native New York home, they were traveling along the California coast with the ultimate stop at Disneyland. Unfamiliar with the roads, Martinez took a wrong turn outside of Fresno and found himself in a less pleasant pa... Read More

NIH-sponsored clinical trial of chikungunya vaccine opens

An experimental vaccine to protect against the mosquito-borne illness chikungunya is being tested in a Phase 2 trial sponsored by the National Institutes of Health. Results from an initial trial of the vaccine, which was developed by scientists at the NIH National Institute of Allergy and Infect... Read More

BacterioFiles 260 - Endoriftia Evacuate Expired Employers

This episode: Bacteria in hydrothermal vents that feed their host tubeworms evacuate when their hosts perish!

(9 MB, 9.8 minutes)

Show notes: 
Journal Paper:

Klose J, Polz MF, Wagner M, Schimak MP, Gollner S, Bright M. 2... Read More

Microbial communication over the airwaves

Jean-Paul Latgé originally wanted to know if he could test the breath of patients with Aspergillus infections for volatile compounds produced by the fungus. His group at the Pasteur Institute in Paris thought this might be a new way of diagnosing fungal culprits like Aspergillus fumigatus that o... Read More

Asymptomatic people can transmit Dengue viruses to Mosquitos

75% of the ~390 million people infected with dengue viruses present with no symptoms (asymptomatic). It is generally assumed that these asymptomatic infections cannot be transmitted to mosquitos. Not only does this study show that people with asymptomatic infections transmitted the virus to mo... Read More

Study finds that Ebola vaccine is safe and stimulates strong immune response

Baltimore, MD, November 17, 2015--A clinical trial of a new Ebola vaccine (ChAd3-EBO-Z) that resulted from an unprecedented global consortium assembled at the behest of the World Health Organization has found that it is well tolerated and stimulates strong immune responses in adults in Mali, Wes... Read More

New American Academy of Microbiology Report provides recommendations for implementing NGS to clinical microbiology settings

This morning, the American Academy of Microbiology released a report, “Applications of Clinical Microbial Next-Generation Sequencing.” An event was held at the National Press Room to highlight its release. You can read more about the event here, or go here to read recommendations on NGS in a cli... Read More

Using citizen science to engage students

Scientists and science educators now recognize the value in explaining what fields don’t understand, in addition to facts supported by years of experimental data. Citizen science projects, which emphasize accessibility of scientific technologies and methods for everyone, allow people without yea... Read More

Vitamin D deficiency may limit immune recovery in HIV-positive adults

Athens, Ga. - A University of Georgia researcher has found that low levels of vitamin D may limit the effectiveness of HIV treatment in adults. Read More

Handprint Culture Shirt

"Everyone Needs a Little Culture" shirt @ Cabrillo College bookstore, 831-479-6209 or Niles Biological, http://www.nilesbio.com/cat499.html Read More

Foot and mouth disease virus: a global threat to agriculture

An important and sometimes overlooked issue of infrastructure is food security. American agriculture and related industries represent $1.5 trillion U.S. dollars and 17% of U.S. jobs. These workers provide the meat, eggs, dairy, and produce that many take for granted will end up on grocery shelve... Read More

Preclinical Studies on the Pharmacokinetics, Safety, and Toxicology of Oxfendazole: Toward First in Human Studies

A number of BZ anthelmintics used in veterinary medicine have been considered for transition to human use, including oxibendazole and oxfendazole (OXF). In addition, flubendazole, already approved for use as an intestinal anthelmintic, is also being developed as a treatment against adult filaria... Read More

Register now for free Mysterious Microbes webinar series starting Jan 14

Want to learn more about the most abundant, diverse, and hidden life on Earth?

Attend the FREE Mysterious Microbes Public Webinar Series and Educator Workshop hosted by CIRES Education Outreach!

These free events feature the cutting-edge research of leading microbial scientist Noah Fierer ... Read More

Nonpathogenic viruses transferred during fecal transplants

Fecal transplants are increasingly being used for refractory Clostridium difficile and other gastrointestinal disorders. While fecal donors are screened for various infectious diseases, it is unclear whether viruses can in fact be transmitted during fecal transplants. Now a new study shows that ... Read More

Microorganisms Spreading Holiday Cheer

This holiday season, as you open a bottle of your favorite wine to share with family and friends, consider making a toast to Saccharomyces cerevisiae (also known as “brewer’s yeast”) which is a species of yeast that is commonly used for making wine and beer. Yeast is absolutely essential to wine... Read More

Microbiomes could hold keys to improving life as we know it

A consortium of 48 scientists from 50 institutions in the United States - including Pamela Silver, Ph.D., a Core Faculty member at the Wyss Institute for Biologically Inspired Engineering at Harvard University - are calling for a Unified Microbiome Initiative that would span national cross-insti... Read More
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