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Bioinspired coating for medical devices repels blood and bacteria

From joint replacements to cardiac implants and dialysis machines, medical devices enhance or save lives on a daily basis. However, any device implanted in the body or in contact with flowing blood faces two critical challenges that can threaten the life of the patient the device is meant to hel... Read More

In Hopes Of Fixing Faulty Genes, One Scientist Starts With The Basics

Whether they admit it or not, many (if not most) scientists secretly hope to get a call in October informing them they've won a Nobel Prize.

But I've talked to a lot of Nobel laureates, and they are unanimous on one point: None of them pursued a research topic with the intention of winning th... Read More

Immune response turned up, not down, by flu during pregnancy

Pregnant women have an unusually strong immune response to influenza, an unexpected finding that may explain why they get sicker from the flu than other healthy adults, new research from the Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford has found.

The ... Read More

Bio-art: The Marriage of Art and Microorganisms

A short interview with artist Selin Balci on her use of microbes as an artistic medium. Here's a quote from the piece on SkyLife.com...

"Bio-art has not yet been defined in a way that is accepted by artists. Some artists, for example, make DNA models and call that BioArt. To me, BioArt has to... Read More

Primitive microbes stole bacterial genes on a surprising scale

A University of Otago researcher is part of an international team that has discovered that horizontal gene transfer (HGT) played a surprisingly large role in the evolution of primitive microbes known as archaea.

HGT, which involves acquiring genetic material from another unrelated organism in... Read More

colony of candida spp.

Colonies of candida species:

Media: HiCrome Candida Differential Agar
principle: Perry and Miller (1) reported that Candida albicans produces an enzyme b -N-acetyl- galactosaminidase and according to
Rousselle et al (2) incorporation of chromogenic or fluorogenic hexosaminidase substrates... Read More

Study reveals how deadly MERS virus enters human cells

Cornell researchers have uncovered details of how the deadly Middle East respiratory syndrome coronavirus (MERS-CoV) enters host cells, findings that help explain how it can infect many cell types – a hallmark of viral pathogenicity. The results also offer possible new avenues for treatment.

... Read More

Bacterial defense policies

High-resolution cryo-electron microscopy has now revealed in unprecedented detail the structural changes in the bacterial ribosome which results in resistance to the antibiotic erythromycin.

Click "source" to read more. Read More

Old drug may be key to new antibiotics

McMaster scientists have found that an anticonvulsant drug may help in developing a new class of antibiotics.

Although dozens of antibiotics target what bacteria do, their study has looked at how a certain part of bacteria are created, and they found there is a way of stopping it.

The disc... Read More

Gut Microbes and Jet Lag, Shift-Work Weight Gain

Disruptions in the human circadian clock can throw off microbes in the gut, potentially boosting the risk of obesity, a new study suggests.

The results may help explain why shift workers and people who get jet lag by traveling frequently often pack on extra pounds.

"These surprising findin... Read More

CDC Launches Ebola Response Team

In the two days since the second U.S. Ebola patient was diagnosed, the U.S. Centers for Disease Control and Prevention (CDC) has assembled a new team to battle the threat of Ebola. This team has no steady lineup, but it will be deployed anywhere in the country that sees a new case of Ebola, CDC ... Read More

Chromosome Organization the Pseudomonas Way, Part 2

Studying chromosome organization in bacteria. Over the last twenty years, molecular biologists developed and refined a downright cute method to study bacterial chromosome organization in live cells. Briefly, a cluster of binding sites for a DNA-binding protein is introduced at a chosen locus of ... Read More

Brazil releases 'good' mosquitoes to fight dengue fever

Brazilian researchers in Rio de Janeiro have released thousands of mosquitoes infected with bacteria that suppress dengue fever.

The hope is they will multiply, breed and become the majority of mosquitoes, thus reducing cases of the disease.

The initiative is part of a programme also takin... Read More

Evolution of extreme parasites explained by scientists

Extreme adaptations of species often cause such significant changes that their evolutionary history is difficult to reconstruct. Zoologists have now discovered a new parasite species that represents the missing link between fungi and an extreme group of parasites. Researchers are now able to und... Read More

Superbugs should scare you more than Ebola in US

The first case of Ebola in the United States was announced today, with a patient in Dallas who traveled to the US from Liberia. The resultant hysteria and xenophobia prompts this reminder. There is NO need to panic.

Ebola is NOT transmitted before a patient develops symptoms. Ebola is transmi... Read More

BDP FL maleimide - BODIPY analog - fluorescent labeling of proteins

BDP FL maleimide
http://www.lumiprobe.com/p/bodipy-fl-maleimide

BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy. BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar... Read More

TWiM 89 Letters

Peter writes:


Dear Michele,


Prof. Szybalski might have been referring to a truck with a wood gas generator


Apparently they are still in use north of the b... Read More

Three Irish Teens Win Google Science Fair Using Bacteria to Grow Food

A trio of Irish high-schoolers nabbed the top prize in this year's Google Science Fair with a project that speeds up crop growth by tapping into the naturally cozy relationship between soil microbes and plants.

After 11 months of experiments, the three 16-year-olds—Ciara Judge, Émer Hickey, a... Read More

Bacterial 'communication system' could be used to stop, kill cancer cells, study finds

Cancer, while always dangerous, truly becomes life-threatening when cancer cells begin to spread to different areas throughout the body. Now, researchers at the University of Missouri have discovered that a molecule used as a communication system by bacteria can be manipulated to prevent cancer ... Read More

Plants prepackage beneficial microbes in their seeds

Plants have a symbiotic relationship with certain bacteria. These 'commensal' bacteria help the plants extract nutrients and defend against invaders -- an important step in preventing pathogens from contaminating fruits and vegetables. Now, scientists have discovered that plants may package thei... Read More
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