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TWiP 116: One drug to rule them all

The TWiPtoids solve the case of the Thai Fisherman with Chronic Diarrhea, and reveal a potential new drug for treatment of leishmaniasis, Chagas diseases, and sleeping sickness.


Hosts: Vincent Racaniel... Read More

Age of the Microzoo

In 3500 BCE, Egyptian rulers built a menagerie of exotic creatures within the ancient capital of Hierakonpolis. Archaeologists have found 112 animal skeletons at this site: the first zoo on Earth. But from this earliest exhibition of the natural world through today’s most famous animal displays,... Read More

Yum! Digesting ASM Resources for Food Microbiology

Food-related microbiology can be one of the most fun - or least fun - ways to interact with microbes. In the ‘most fun’ category, scientists and non-scientists alike can use microbes to create delicious foods from fermentative processes; in the ‘least fun’ category, scientists and non-scientists... Read More

TWiV 407: Tar Heels go viral, part two

In the second of two shows recorded at the University of North Carolina in Chapel Hill, Vincent meets up with faculty members to talk about how they got into science, their research on RNA viruses, and what they would be doing if they were not scientists.


Host:  Read More

ASM Announces Tools to Help Authors and Reviewers Alike

Communication of experimental results via publishing is one of the most important steps of the scientific method; if you don’t share your results, how will knowledge within a field grow? A well-written article contextualizes the author’s data into a broader scientific landscape, which allows rea... Read More

BacterioFiles 267 - Crust Color Cooks Communities

This episode: Cyanobacteria in biocrusts produce pigments that heat their surroundings up to 10 degrees hotter!


(7 MB, 7.6 minutes)


Show notes: 
Read More

Fitness landscapes for microbial pathogens in agricultural systems

How is it that we are we able to devote so little of our personal time and energy to producing or acquiring the healthy, safe food that we consume multiple times every day? A large part of the reason we seldom worry about agricultural output is that most of us benefit enormously from modernized,... Read More

TWiV 406: Pow, right in the enteroids!

The TWiV team discusses eye infections caused by Zika virus, failure of Culex mosquitoes to transmit the virus, and replication of norovirus in stem cell derived enteroids.


Hosts:  Read More

BacterioFiles 268 - Sophisticated Cyanobacterium Sight

This episode: Spherical cyanobacterium Synechocystis acts like a tiny eyeball in sensing light, allowing cells to move closer to light sources!


(9.7 MB, 10.6 minutes)


Show notes: synSEM Read More

Getting the hologenome concept right

Given the complexity of host-microbiota symbioses, scientists and philosophers are asking questions at new biological levels of hierarchical organization—what is a holobiont and hologenome? When should this vocabulary be applied? Are these concepts a null hypothesis for host-microbe systems or l... Read More

Leaf Flora

Bacillus mycoides and other bacteria growing from a leaf placed on nutrient agar after 3 days incubation.
(South West England) Read More

PROTEUS

PROTEUS swarming in BG agar, Just beautiful. Read More

Interview with Neal Nathanson, MD - Principles of Virology, 4th Edition

Vincent Racaniello of the This Week in Virology podcast interviews Neal Nathanson, MD, about his career and professional experience in the field of virology. Nathanson's work has focused on the epidemiology and eradication of poliomyelitis, the control of the HIV/AIDS pandemic and the developmen... Read More

"The Amazing Adventures of the Virologists” Part One - Vaccines _ 6

"Hivi and his team of viruses (Ebola, Pox,..etc) believe they can win the battle, but the Virologists (who are real famous professors) beat them. However, new viruses pop-up, it will be a long battle. This makes the story very interesting and ever so engaging."
==================
ACKNOWLEDGMEN... Read More

Earliest Signs Of Animal Life May Be From Microbes

Evidence suggests that microbes existed on Earth as far back as 3.7 billion years ago, a billion years after the planet formed. Animal remains, however, don't appear in the fossil record until 600 million years ago during the Ediacaran period, though there are indirect signs that animal life may... Read More

Sabotaging bacteria propellers to stop infections

Researchers at the Okinawa Institute of Science and Technology Graduate University in Japan are exploring the possibility of disrupting infections by modifying the flagella of infected bacteria. They are doing this by modifying a protein outside of the bacteria and then re-inserting into the ba... Read More

Pic of the day - Acremonium strictum

Acremonium strictum grown on Potato Dextrose Agar Read More

TWiM 135 Letters

Reed writes:


Dear Vincent, Elio, Michael, and Michelle,


I've just recently finished TWiM number 133 and wanted to comment about the use of the term "secondary metabolite" throughout the episode and often in the primary literature. Michael pointed out that a se... Read More

A Cinematic Approach to Antibiotic Resistance

In a creative stroke inspired by Hollywood wizardry, Harvard scientists have designed a simple way to observe how bacteria move as they become impervious to drugs. The experiments are thought to provide the first large-scale glimpse of the maneuvers of bacteria as they encounter increasingly hig... Read More

Santiria apiculata rhizosphere fungi from UKM forest reserve.

Fungi from Santiria apiculata rhizosphere grown on water agar, 14 days incubation period. With the same morphological appearances, there is a strong cross communication, thus creating zones of inhibition. Read More
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