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TWiM #96: A lean, mean sequencing machine

Hosts: Vincent Racaniello.


Special guest: Rob Knight


Vincent meets up with Rob Knight to talk about the technology that ha... Read More

Serpentine cording in Mycobacterium tuberculosus

Pictured is a culture of Mycobacterium tuberculosis growing colonies in the distinctive "serpentine cord" form seen in many strains of M. tuberculosis. These cords are made up of chains of cells that make chains due to a cell wall factor of MTB.

The cell wall structure of Mycobacterium is a m... Read More

Bacillus/Diplobacillus

Simple stain done on an unknown bacteria, showing feathery rhizoid growth on TSA after a 48 hr incubation at 37 degree’s C, isolated from a floor swab. Single bacillus and diplobacillus can be seen though out. Read More

New Species Discovered Beneath Ocean Crust

Two miles below the surface of the ocean, researchers have discovered new microbes that “breathe” sulfate.

The microbes, which have yet to be classified and named, exist in massive undersea aquifers — networks of channels in porous rock beneath the ocean where water continually churns. About ... Read More

Harnessing bacteria to move microscopic gears and ratchets

Previous research has already demonstrated that substantial quantities of self-motile or active agents such as bacteria in a fluid environment can be harnessed to do mechanical work like moving microscopic gears and ratchets. Bacteria as well as algae can also be used to transport or displace ma... Read More

Ancient Viruses Gain New Functions in the Brain

If thinking about the billions of bacteria taking up residence in and on your body gives you the willies, you probably won’t find it comforting that humans are also full of viruses. These maligned microbes are actually intertwined in the very fibers of our being—about 8 percent of our genetic ma... Read More

Viroids, infectious agents that encode no proteins

Genomes of non-defective viruses range in size from 2,400,000 bp of dsDNA (Pandoravirus salinus) to 1,759 bp of ssDNA (porcine circovirus). Are even smaller viral genomes possible? The subviral agents called viroids provide an answer to this question.

Viroids, the smallest known pathogens, ar... Read More

E. coli gram stain

Gram stain of E. coli showing characteristic G- rods. Read More
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