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Gut Bacteria Lose their Tails to Evade Antibodies

New research reveals the complex dynamic between gut bacteria and the immune system that keeps proteins from flagellin—bacterial tails—under control.

In healthy individuals, the only thing that separates the lining of the human gut from the some 100 trillion bacterial cells in the gastrointes... Read More

Pictures Considered #11. Invisible Portraits: A Microbial Art Exhibit

Getting the message out to the public that the microbial world is about much more than just diseases is a challenging topic, but one we should keep trying to improve on. There are many ways to do this, but as the saying goes, a picture is worth a thousand words, and most people don’t want to rea... Read More

Molecular mechanisms of resistance

The abilities of bacterial organisms to utilize the various strategies to resist antimicrobial compounds are all genetically encoded.

Intrinsic resistance is that type of resistance which is naturally coded and expressed by all (or almost all) strains of that particular bacterial species. An... Read More

Reduced glycopeptide and lipopeptide susceptibility in Staphylococcus aureus and the “seesaw effect”: Taking advantage of the back door left open?

Methicillin-resistant S. aureus (MRSA) constitutes approximately 50% of clinical S. aureus isolates and is most commonly the result of production of a mutated pencillin-binding protein, PBP2a, which is able to carry out essential cell wall synthesis functions while maintaining a low-affinity for... Read More

Facilitation of horizontal transfer of antimicrobial resistance by transformation of antibiotic-induced cell-wall-deficient bacteria

It is universally accepted that the use of antibiotics will lead to antimicrobial resistance. Traditionally, the explanation to this phenomenon was random mutation and horizontal gene transfer and amplification by selective pressure. Subsequently, a second mechanism of antibiotic-induced antimic... Read More

Clinically Important Drug-Resistant Bacteria” .

"Clinically Important Drug-Resistant Bacteria” Read More

Antibiotic resistance mechanisms of clinically important bacteria.

Antibiotic resistance mechanisms of clinically important bacteria. Read More

Genomes provide clues for treating leukemia, endometrial cancers

Genomes provide clues for treating leukemia, endometrial cancers

Read More

In order to track norovirus, UK authorities would like you to tweet the color of your vomit

The phrase "Twitter feed" is about to take on a troubling hue. The Food Standards Authority would like all British citizens... to keep it up to date with the color of their vomit and much more.

The government wants to keep abreast of the norovirus. This virus -- known in the UK as the winter ... Read More

Inactivation of antibiotics and the dissemination of resistance genes

Inactivation of antibiotics and the dissemination of resistance genes Read More

Symbiosis: A New Synthesis

Darwin and the 20th century pioneers of biology would have been astonished to see the countless roles that microbes play in shaping eukaryotic life. From the origins of eukaryotic cells to pharmaceutical products, Life as we know it would be unrecognizable without microbes. Integrating microbes ... Read More

Bacterial Bubble Hitchhikers Could Help Keep Greenhouse Gas in Check

Seafloor-dwelling bacteria may hitch a ride on methane bubbles seeping from deep-sea vents, preventing the methane from reaching the atmosphere by eating it up, new research suggests.

The findings, presented here today (Dec. 9) at the annual meeting of the American Geophysical Union, could he... Read More

In surprise finding, blood clots absorb bacterial toxin

Blood clots play an unexpected role in protecting the body from the deadly effects of bacteria by absorbing bacterial toxins, researchers at the University of California, Davis, have found. The research was published Dec. 2 in the journal PLoS ONE.

"It's a significant addition to the short li... Read More

Penicillin equally effective as ‘big gun’ antibiotics for treating less severe childhood pneumonia

Children hospitalized for pneumonia have similar outcomes, including length of stay and costs, regardless of whether they are treated with “big gun” antibiotics such as ceftriaxone or cefotaxime or more narrowly focused antibiotics such as ampicillin or penicillin, according to a Vanderbilt stud... Read More

Microbiome Candy: Could A Probiotic Mint Help Prevent Cavities?

Eat candy and fight tooth decay. What a sweet concept, right?

Well, microbiologists in Berlin are trying to make that dream a reality.

They've created a sugarless mint that's aimed at washing out cavity-causing bacteria from your mouth. And the candy works in a curious way: It's spiked wit... Read More

Scientists explore the mechanisms of viruses' shells

The genome of viruses is usually enclosed inside a shell called capsid. Capsids have unique mechanic properties: they have to be resistant and at the same time capable of dissolving in order to release the genome into the infected cell. The scientists of the International School for Advanced Stu... Read More

Handling the cholera outbreak of 1854

This article discusses the famous pump handle that John Snow may or may not have had removed ... read the article to get the true story. From medical historian Peter Vinten-Johansen. Read More

BacterioFiles Micro Edition 146 - Engineered Escherichia Eliminates Enemies

This episode: Scientists engineered E. coli to seek and destroy pathogens!


(10 MB, 11 minutes)


A bacterium can sense pathogens in the body, swim toward them, and release a deadly biofilm-busting payload. This process is called pseudotaxis, and could be modified for many... Read More

Better preparedness against Tamiflu-resistant influenza viruses

Researchers in Umeå and Uppsala have found that residues of the influenza drug Tamiflu in our environment can make the influenza virus in birds resistant. This can have serious consequences in the event of an influenza pandemic. With more than 14 million SEK from the Swedish Research Councils Fo... Read More

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